Congenital fetal heart defect - an agreement between fetal echocardiography and autopsy findings

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F20%3AN0000202" target="_blank" >RIV/00098892:_____/20:N0000202 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00179906:_____/20:10420292 RIV/00843989:_____/20:E0108407

Výsledek na webu

<a href="https://biomed.papers.upol.cz/pdfs/bio/2020/01/11.pdf" target="_blank" >https://biomed.papers.upol.cz/pdfs/bio/2020/01/11.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2019.042" target="_blank" >10.5507/bp.2019.042</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Congenital fetal heart defect - an agreement between fetal echocardiography and autopsy findings

Popis výsledku v původním jazyce

Aims. To determine the frequency of pregnancy terminations due to prenatal congenital heart defect (CHD) and assess the agreement fetal chocardiography (FECHO) and autopsy findings. Methods. The data were retrospectively assessed between 2008 and 2017 in a population of 116 698 live births. The correlations between the FECHO and autopsy findings were classified into five levels of agreement: complete, partial, altered diagnosis, disagreement, and unfeasible autopsy. Results. Totally, 293 CHDs were identified and 49% of families (143/293) decided to terminate the pregnancy. In 1% (2/143) of cases, the autopsy could not be performed, for the other 99% (141/143), the pathologist confirmed the presence of CHDs. Complete agreement between FECHO and autopsy was achieved in 85% (122/143). In 10% (14/143) of cases, the pathologist found minor findings, which were not described in the FECHO. In 4% (5/143) of cases, the pathologist changed the main diagnosis. Conclusion. Altogether, the results indicated that FECHO is a highly sensitive method for the prenatal detection of CHD but is incapable of detecting the complete spectrum of cardiac defects. Autopsies verified the diagnosis, confirmed the overall impairment in the fetus, and provided data for further counselling of the affected family.

Název v anglickém jazyce

Congenital fetal heart defect - an agreement between fetal echocardiography and autopsy findings

Popis výsledku anglicky

Aims. To determine the frequency of pregnancy terminations due to prenatal congenital heart defect (CHD) and assess the agreement fetal chocardiography (FECHO) and autopsy findings. Methods. The data were retrospectively assessed between 2008 and 2017 in a population of 116 698 live births. The correlations between the FECHO and autopsy findings were classified into five levels of agreement: complete, partial, altered diagnosis, disagreement, and unfeasible autopsy. Results. Totally, 293 CHDs were identified and 49% of families (143/293) decided to terminate the pregnancy. In 1% (2/143) of cases, the autopsy could not be performed, for the other 99% (141/143), the pathologist confirmed the presence of CHDs. Complete agreement between FECHO and autopsy was achieved in 85% (122/143). In 10% (14/143) of cases, the pathologist found minor findings, which were not described in the FECHO. In 4% (5/143) of cases, the pathologist changed the main diagnosis. Conclusion. Altogether, the results indicated that FECHO is a highly sensitive method for the prenatal detection of CHD but is incapable of detecting the complete spectrum of cardiac defects. Autopsies verified the diagnosis, confirmed the overall impairment in the fetus, and provided data for further counselling of the affected family.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Papers-Olomouc  

ISSN

1213-8118

e-ISSN

1804-7521

Svazek periodika

164

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

92-99

Kód UT WoS článku

000528221900011

EID výsledku v databázi Scopus

2-s2.0-85082563459