Development and performance assessment of an advanced Lucas-Kanade algorithm for dose mapping of cervical cancer external radiotherapy and brachytherapy plans

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F21%3AN0000126" target="_blank" >RIV/00098892:_____/21:N0000126 - isvavai.cz</a>

Výsledek na webu

<a href="https://aapm.onlinelibrary.wiley.com/doi/10.1002/acm2.13249" target="_blank" >https://aapm.onlinelibrary.wiley.com/doi/10.1002/acm2.13249</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/acm2.13249" target="_blank" >10.1002/acm2.13249</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Development and performance assessment of an advanced Lucas-Kanade algorithm for dose mapping of cervical cancer external radiotherapy and brachytherapy plans

Popis výsledku v původním jazyce

Purpose: The aim of this study was to verify the possibility of summing the dose distributions of combined radiotherapeutic treatment of cervical cancer using the extended Lucas-Kanade algorithm for deformable image registration. Materials and methods: First, a deformable registration of planning computed tomography images for the external radiotherapy and brachytherapy treatment of 10 patients with different parameter settings of the Lucas-Kanade algorithm was performed. By evaluating the registered data using landmarks distance, root mean square error of Hounsfield units and 2D gamma analysis, the optimal parameter values were found. Next, with another group of 10 patients, the accuracy of the dose mapping of the optimized Lucas-Kanade algorithm was assessed and compared with Horn-Schunck and modified Demons algorithms using dose differences at landmarks. Results: The best results of the Lucas-Kanade deformable registration were achieved for two pyramid levels in combination with a window size of 3 voxels. With this registration setting, the average landmarks distance was 2.35 mm, the RMSE was the smallest and the average gamma score reached a value of 86.7%. The mean dose difference at the landmarks after mapping the external radiotherapy and brachytherapy dose distributions was 1.33 Gy. A statistically significant difference was observed on comparing the Lucas-Kanade method with the Horn-Schunck and Demons algorithms, where after the deformable registration, the average difference in dose was 1.60 Gy (P-value: 0.0055) and 1.69 Gy (P-value: 0.0012), respectively. Conclusion: Lucas-Kanade deformable registration can lead to a more accurate model of dose accumulation and provide a more realistic idea of the dose distribution.

Název v anglickém jazyce

Development and performance assessment of an advanced Lucas-Kanade algorithm for dose mapping of cervical cancer external radiotherapy and brachytherapy plans

Popis výsledku anglicky

Purpose: The aim of this study was to verify the possibility of summing the dose distributions of combined radiotherapeutic treatment of cervical cancer using the extended Lucas-Kanade algorithm for deformable image registration. Materials and methods: First, a deformable registration of planning computed tomography images for the external radiotherapy and brachytherapy treatment of 10 patients with different parameter settings of the Lucas-Kanade algorithm was performed. By evaluating the registered data using landmarks distance, root mean square error of Hounsfield units and 2D gamma analysis, the optimal parameter values were found. Next, with another group of 10 patients, the accuracy of the dose mapping of the optimized Lucas-Kanade algorithm was assessed and compared with Horn-Schunck and modified Demons algorithms using dose differences at landmarks. Results: The best results of the Lucas-Kanade deformable registration were achieved for two pyramid levels in combination with a window size of 3 voxels. With this registration setting, the average landmarks distance was 2.35 mm, the RMSE was the smallest and the average gamma score reached a value of 86.7%. The mean dose difference at the landmarks after mapping the external radiotherapy and brachytherapy dose distributions was 1.33 Gy. A statistically significant difference was observed on comparing the Lucas-Kanade method with the Horn-Schunck and Demons algorithms, where after the deformable registration, the average difference in dose was 1.60 Gy (P-value: 0.0055) and 1.69 Gy (P-value: 0.0012), respectively. Conclusion: Lucas-Kanade deformable registration can lead to a more accurate model of dose accumulation and provide a more realistic idea of the dose distribution.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30224 - Radiology, nuclear medicine and medical imaging

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Applied Clinical Medical Physics

ISSN

1526-9914

e-ISSN

1526-9914

Svazek periodika

22

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

69-78

Kód UT WoS článku

000646677500001

EID výsledku v databázi Scopus

2-s2.0-85105643407