The Role of Tumor Microenvironment and Immune Response in Colorectal Cancer Development and Prognosis
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F22%3A10157511" target="_blank" >RIV/00098892:_____/22:10157511 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61989592:15110/22:73615808
Výsledek na webu
<a href="https://www.por-journal.com/articles/10.3389/pore.2022.1610502/full" target="_blank" >https://www.por-journal.com/articles/10.3389/pore.2022.1610502/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/pore.2022.1610502" target="_blank" >10.3389/pore.2022.1610502</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The Role of Tumor Microenvironment and Immune Response in Colorectal Cancer Development and Prognosis
Popis výsledku v původním jazyce
Colorectal cancer (CRC) is one of the most common cancers worldwide. The patient's prognosis largely depends on the tumor stage at diagnosis. The pathological TNM Classification of Malignant Tumors (pTNM) staging of surgically resected cancers represents the main prognostic factor and guidance for decision-making in CRC patients. However, this approach alone is insufficient as a prognostic predictor because clinical outcomes in patients at the same histological tumor stage can still differ. Recently, significant progress in the treatment of CRC has been made due to improvements in both chemotherapy and surgical management. Immunotherapy-based approaches are one of the most rapidly developing areas of tumor therapy. This review summarizes the current knowledge about the tumor microenvironment (TME), immune response and its interactions with CRC development, immunotherapy and prognosis.
Název v anglickém jazyce
The Role of Tumor Microenvironment and Immune Response in Colorectal Cancer Development and Prognosis
Popis výsledku anglicky
Colorectal cancer (CRC) is one of the most common cancers worldwide. The patient's prognosis largely depends on the tumor stage at diagnosis. The pathological TNM Classification of Malignant Tumors (pTNM) staging of surgically resected cancers represents the main prognostic factor and guidance for decision-making in CRC patients. However, this approach alone is insufficient as a prognostic predictor because clinical outcomes in patients at the same histological tumor stage can still differ. Recently, significant progress in the treatment of CRC has been made due to improvements in both chemotherapy and surgical management. Immunotherapy-based approaches are one of the most rapidly developing areas of tumor therapy. This review summarizes the current knowledge about the tumor microenvironment (TME), immune response and its interactions with CRC development, immunotherapy and prognosis.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30204 - Oncology
Návaznosti výsledku
Projekt
<a href="/cs/project/NU21-03-00372" target="_blank" >NU21-03-00372: Malé vazebné proteiny cílené na proteiny imunitní kontrolní dráhy PD-1/PD-L1 jako nové diagnostické nástroje</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2022
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
PATHOLOGY & ONCOLOGY RESEARCH
ISSN
1219-4956
e-ISSN
1532-2807
Svazek periodika
28
Číslo periodika v rámci svazku
July
Stát vydavatele periodika
CH - Švýcarská konfederace
Počet stran výsledku
12
Strana od-do
1610502
Kód UT WoS článku
000872915300001
EID výsledku v databázi Scopus
2-s2.0-85135522745