High-normal blood pressure is associated with increased resting sympathetic activity but normal responses to stress tests

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F13%3A00060553" target="_blank" >RIV/00159816:_____/13:00060553 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.3109/08037051.2012.759689" target="_blank" >http://dx.doi.org/10.3109/08037051.2012.759689</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3109/08037051.2012.759689" target="_blank" >10.3109/08037051.2012.759689</a>

Jazyk výsledku

angličtina

Název v původním jazyce

High-normal blood pressure is associated with increased resting sympathetic activity but normal responses to stress tests

Popis výsledku v původním jazyce

High-normal blood pressure (BP) increases the risk of cardiovascular (CV) disease. The mechanisms underlying this increased risk are not clear. Sympathetic activation appears to be a potential mechanism linking high-normal BP to CV disease. This study examined whether high-normal BP compared with optimal BP is linked to sympathoexcitation at rest and/or during laboratory stressors. Methods. Heart rate (HR), BP and muscle sympathetic nerve activity (MSNA) were obtained at rest and during stress tests (sustained handgrip and mental stress) in 18 subjects (15 males and three females) with high-normal BP (systolic BP of 130 -139 mmHg, diastolic BP of 85 -89 mmHg, or both) and in 12 subjects (10 males and two females) with optimal BP (<120/80 mmHg) matchedfor age (34 +/- 3 years in both groups) and body mass index (25 +/- 2 kg/m(2) in both groups). Results. Despite the higher resting BP levels, MSNA was higher in subjects with high-normal BP than in the optimal BP group (26 +/- 3 vs 18 +/-

Název v anglickém jazyce

High-normal blood pressure is associated with increased resting sympathetic activity but normal responses to stress tests

Popis výsledku anglicky

High-normal blood pressure (BP) increases the risk of cardiovascular (CV) disease. The mechanisms underlying this increased risk are not clear. Sympathetic activation appears to be a potential mechanism linking high-normal BP to CV disease. This study examined whether high-normal BP compared with optimal BP is linked to sympathoexcitation at rest and/or during laboratory stressors. Methods. Heart rate (HR), BP and muscle sympathetic nerve activity (MSNA) were obtained at rest and during stress tests (sustained handgrip and mental stress) in 18 subjects (15 males and three females) with high-normal BP (systolic BP of 130 -139 mmHg, diastolic BP of 85 -89 mmHg, or both) and in 12 subjects (10 males and two females) with optimal BP (<120/80 mmHg) matchedfor age (34 +/- 3 years in both groups) and body mass index (25 +/- 2 kg/m(2) in both groups). Results. Despite the higher resting BP levels, MSNA was higher in subjects with high-normal BP than in the optimal BP group (26 +/- 3 vs 18 +/-

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Blood pressure

ISSN

0803-7051

e-ISSN

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Svazek periodika

22

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

183-187

Kód UT WoS článku

000318807100010

EID výsledku v databázi Scopus

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