Midlife alcohol consumption and risk of dementia over 43 years of follow up: A population-based study from the Swedish Twin Registry
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F15%3A00062992" target="_blank" >RIV/00159816:_____/15:00062992 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1093/gerona/glv038" target="_blank" >http://dx.doi.org/10.1093/gerona/glv038</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/gerona/glv038" target="_blank" >10.1093/gerona/glv038</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Midlife alcohol consumption and risk of dementia over 43 years of follow up: A population-based study from the Swedish Twin Registry
Popis výsledku v původním jazyce
BACKGROUND: Midlife alcohol consumption (beer, wine, and spirits) was examined in relation to dementia incidence over 43 years. METHODS: Participants were 12,326 members of the population-based Swedish Twin Registry born during 1907-1925 who responded toitems about alcohol consumption in 1967/1970, subsequently classified as nondrinking (0 grams of ethanol per day), light (1-5g/d), moderate (5-12g/d), heavy (12-24g/d), and very heavy (>24g/d) drinking. Dementia was identified from the National Patientand Cause of Death Registries. Cox proportional hazard models adjusted for cluster-correlated data were used in cohort analyses. Conditional logistic regression (dementia-discordant pairs) and mixed effects models (dementia-concordant pairs) were used intwin analyses. RESULTS: Overall, nondrinkers did not differ from light drinkers in dementia risk. Heavy drinking (hazard ratio = 1.10, p = .028) and very heavy drinking (hazard ratio = 1.18, p = .033) were associated with increased demen
Název v anglickém jazyce
Midlife alcohol consumption and risk of dementia over 43 years of follow up: A population-based study from the Swedish Twin Registry
Popis výsledku anglicky
BACKGROUND: Midlife alcohol consumption (beer, wine, and spirits) was examined in relation to dementia incidence over 43 years. METHODS: Participants were 12,326 members of the population-based Swedish Twin Registry born during 1907-1925 who responded toitems about alcohol consumption in 1967/1970, subsequently classified as nondrinking (0 grams of ethanol per day), light (1-5g/d), moderate (5-12g/d), heavy (12-24g/d), and very heavy (>24g/d) drinking. Dementia was identified from the National Patientand Cause of Death Registries. Cox proportional hazard models adjusted for cluster-correlated data were used in cohort analyses. Conditional logistic regression (dementia-discordant pairs) and mixed effects models (dementia-concordant pairs) were used intwin analyses. RESULTS: Overall, nondrinkers did not differ from light drinkers in dementia risk. Heavy drinking (hazard ratio = 1.10, p = .028) and very heavy drinking (hazard ratio = 1.18, p = .033) were associated with increased demen
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FQ - Veřejné zdravotnictví, sociální lékařství
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: Fakultní nemocnice u sv. Anny v Brně - Mezinárodní centrum klinického výzkumu (FNUSA - ICRC)</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of Gerontology Series A-Biological Sciences and Medical Sciences
ISSN
1079-5006
e-ISSN
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Svazek periodika
70
Číslo periodika v rámci svazku
10
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
7
Strana od-do
1248-1254
Kód UT WoS článku
000363481600010
EID výsledku v databázi Scopus
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