Use of micro computed-tomography and 3D printing for reverse engineering of mouse embryo nasal capsule

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F16%3A00065178" target="_blank" >RIV/00159816:_____/16:00065178 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/16:00090163 RIV/00216305:26620/16:PU118248

Výsledek na webu

<a href="http://dx.doi.org/10.1088/1748-0221/11/03/C03006" target="_blank" >http://dx.doi.org/10.1088/1748-0221/11/03/C03006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1088/1748-0221/11/03/C03006" target="_blank" >10.1088/1748-0221/11/03/C03006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Use of micro computed-tomography and 3D printing for reverse engineering of mouse embryo nasal capsule

Popis výsledku v původním jazyce

Imaging of increasingly complex cartilage in vertebrate embryos is one of the key tasks of developmental biology. This is especially important to study shape-organizing processes during initial skeletal formation and growth. Advanced imaging techniques that are reflecting biological needs give a powerful impulse to push the boundaries of biological visualization. Recently, techniques for contrasting tissues and organs have improved considerably, extending traditional 2D imaging approaches to 3D. X-ray micro computed tomography (mu CT), which allows 3D imaging of biological objects including their internal structures with a resolution in the micrometer range, in combination with contrasting techniques seems to be the most suitable approach for non-destructive imaging of embryonic developing cartilage. Despite there are many software-based ways for visualization of 3D data sets, having a real solid model of the studied object might give novel opportunities to fully understand the shape-organizing processes in the developing body. In this feasibility study we demonstrated the full procedure of creating a real 3D object of mouse embryo nasal capsule, i.e. the staining, the mu CT scanning combined by the advanced data processing and the 3D printing.

Název v anglickém jazyce

Use of micro computed-tomography and 3D printing for reverse engineering of mouse embryo nasal capsule

Popis výsledku anglicky

Imaging of increasingly complex cartilage in vertebrate embryos is one of the key tasks of developmental biology. This is especially important to study shape-organizing processes during initial skeletal formation and growth. Advanced imaging techniques that are reflecting biological needs give a powerful impulse to push the boundaries of biological visualization. Recently, techniques for contrasting tissues and organs have improved considerably, extending traditional 2D imaging approaches to 3D. X-ray micro computed tomography (mu CT), which allows 3D imaging of biological objects including their internal structures with a resolution in the micrometer range, in combination with contrasting techniques seems to be the most suitable approach for non-destructive imaging of embryonic developing cartilage. Despite there are many software-based ways for visualization of 3D data sets, having a real solid model of the studied object might give novel opportunities to fully understand the shape-organizing processes in the developing body. In this feasibility study we demonstrated the full procedure of creating a real 3D object of mouse embryo nasal capsule, i.e. the staining, the mu CT scanning combined by the advanced data processing and the 3D printing.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FS - Lékařská zařízení, přístroje a vybavení

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Instrumentation

ISSN

1748-0221

e-ISSN

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Svazek periodika

11

Číslo periodika v rámci svazku

MAR

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

12

Strana od-do

"C03006"

Kód UT WoS článku

000375746200008

EID výsledku v databázi Scopus

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