CPAP with Pressure Relief during Exhalation (C-Flex ) is as Effective as CPAP in the Treatment of Obstructive Sleep Apnea

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067029" target="_blank" >RIV/00159816:_____/17:00067029 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.4172/2167-0277.1000268" target="_blank" >http://dx.doi.org/10.4172/2167-0277.1000268</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4172/2167-0277.1000268" target="_blank" >10.4172/2167-0277.1000268</a>

Jazyk výsledku

angličtina

Název v původním jazyce

CPAP with Pressure Relief during Exhalation (C-Flex ) is as Effective as CPAP in the Treatment of Obstructive Sleep Apnea

Popis výsledku v původním jazyce

Purpose: Continuous positive airway pressure (CPAP) is the accepted therapy for obstructive sleep apnea (OSA). An expiratory pressure relief technology called C-Flex+ has been developed to improve the comfort of CPAP therapy. It provides a 2 mbar lower exhalation pressure and an additional flow-based pressure relief at the beginning of exhalation. The following study was conducted to investigate whether C-Flex+ was as effective as CPAP in treating OSA, and the patients&apos; preference. Methods: 60 newly diagnosed patients with OSA completed this double-blind controlled crossover-study. Patients were randomized to one night of C-Flex+ and one of CPAP under full attended polysomnography (PSG). A comfort visual analog scale (VAS) ranging from 0 to 10, with 10 being the highest comfort, was completed by all patients immediately after each PSG. Results: There was no significant difference between the therapy modes in the apnea/hypopnea index (median 1.5 events/hour (h) with C-Flex+ (interquartile range (IQR) 0.7 to 3.6) vs. 1.7 events/h with CPAP (IQR 0.8 to 3.8), p=0.178). The sleep efficiency, sleep architecture and nocturnal oxygenation were also comparable. Most patients preferred C-Flex+ over CPAP (65%, p&lt;0.001). C-Flex+ earned significantly higher ratings in the VAS (8.1 (7.2 to 9.0) vs. 7.0 (5.1 to 8.8), p&lt;0.001).

Název v anglickém jazyce

CPAP with Pressure Relief during Exhalation (C-Flex ) is as Effective as CPAP in the Treatment of Obstructive Sleep Apnea

Popis výsledku anglicky

Purpose: Continuous positive airway pressure (CPAP) is the accepted therapy for obstructive sleep apnea (OSA). An expiratory pressure relief technology called C-Flex+ has been developed to improve the comfort of CPAP therapy. It provides a 2 mbar lower exhalation pressure and an additional flow-based pressure relief at the beginning of exhalation. The following study was conducted to investigate whether C-Flex+ was as effective as CPAP in treating OSA, and the patients&apos; preference. Methods: 60 newly diagnosed patients with OSA completed this double-blind controlled crossover-study. Patients were randomized to one night of C-Flex+ and one of CPAP under full attended polysomnography (PSG). A comfort visual analog scale (VAS) ranging from 0 to 10, with 10 being the highest comfort, was completed by all patients immediately after each PSG. Results: There was no significant difference between the therapy modes in the apnea/hypopnea index (median 1.5 events/hour (h) with C-Flex+ (interquartile range (IQR) 0.7 to 3.6) vs. 1.7 events/h with CPAP (IQR 0.8 to 3.8), p=0.178). The sleep efficiency, sleep architecture and nocturnal oxygenation were also comparable. Most patients preferred C-Flex+ over CPAP (65%, p&lt;0.001). C-Flex+ earned significantly higher ratings in the VAS (8.1 (7.2 to 9.0) vs. 7.0 (5.1 to 8.8), p&lt;0.001).

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

<a href="/cs/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: Fakultní nemocnice u sv. Anny v Brně - Mezinárodní centrum klinického výzkumu (FNUSA - ICRC)</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Sleep Disorders &amp; Therapy

ISSN

2167-0277

e-ISSN

—

Svazek periodika

6

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

1000268

Kód UT WoS článku

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EID výsledku v databázi Scopus

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