Lack of Association between BMP2/DLX3 Gene Polymorphisms and Dental Caries in Primary and Permanent Dentitions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067318" target="_blank" >RIV/00159816:_____/17:00067318 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/17:00095175

Výsledek na webu

<a href="http://dx.doi.org/10.1159/000479828" target="_blank" >http://dx.doi.org/10.1159/000479828</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1159/000479828" target="_blank" >10.1159/000479828</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Lack of Association between BMP2/DLX3 Gene Polymorphisms and Dental Caries in Primary and Permanent Dentitions

Popis výsledku v původním jazyce

The aim of this study was to analyze the association between BMP2 (rs1884302) and DLX3 (rs2278163) gene polymorphisms and dental caries in primary and permanent dentitions. A total of 914 subjects were genotyped by the TaqMan methods: 176 caries-free children (with Decayed/Missing/Filled Teeth, DMFT = 0), 542 patients with dental caries in permanent dentition (DMFT GREATER-THAN OR EQUAL TO1), 83 caries-free children with primary teeth (with decayed/missing/filled teeth, dmft = 0), and 113 children with early childhood caries (ECC, dmft GREATER-THAN OR EQUAL TO1). There were no significant differences in allele/genotype frequencies between patients with caries in permanent dentition/ECC and caries-free children or between patients with very low (DMFT = 0-2), low (DMFT = 3-5), moderate (DMFT = 6-8), or high (DMFT GREATER-THAN OR EQUAL TO9) caries experience. Variability in BMP2 and DLX3 was not associated with caries in the Czech population.

Název v anglickém jazyce

Lack of Association between BMP2/DLX3 Gene Polymorphisms and Dental Caries in Primary and Permanent Dentitions

Popis výsledku anglicky

The aim of this study was to analyze the association between BMP2 (rs1884302) and DLX3 (rs2278163) gene polymorphisms and dental caries in primary and permanent dentitions. A total of 914 subjects were genotyped by the TaqMan methods: 176 caries-free children (with Decayed/Missing/Filled Teeth, DMFT = 0), 542 patients with dental caries in permanent dentition (DMFT GREATER-THAN OR EQUAL TO1), 83 caries-free children with primary teeth (with decayed/missing/filled teeth, dmft = 0), and 113 children with early childhood caries (ECC, dmft GREATER-THAN OR EQUAL TO1). There were no significant differences in allele/genotype frequencies between patients with caries in permanent dentition/ECC and caries-free children or between patients with very low (DMFT = 0-2), low (DMFT = 3-5), moderate (DMFT = 6-8), or high (DMFT GREATER-THAN OR EQUAL TO9) caries experience. Variability in BMP2 and DLX3 was not associated with caries in the Czech population.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30208 - Dentistry, oral surgery and medicine

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Caries Research

ISSN

0008-6568

e-ISSN

—

Svazek periodika

2017

Číslo periodika v rámci svazku

51

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

6

Strana od-do

590-595

Kód UT WoS článku

000419790800006

EID výsledku v databázi Scopus

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