Measurement of blood filling in lower limbs by bioimpedance method

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F17%3A00067629" target="_blank" >RIV/00159816:_____/17:00067629 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26220/17:PU136940

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Measurement of blood filling in lower limbs by bioimpedance method

Popis výsledku v původním jazyce

Background: Cardiovascular diseases are the leading causes of mortality and morbidity in modern society. The autonomic nervous systems innervate blood vessel walls and regulate contraction and wall tension. The head-up tilt test is frequently performed for evaluating sympathetic nervous system function. The filling of the lower extremities during the head-up tilt test is measured by the bioimpedance method. Increased blood volume in the area of interest increases the electrical impedance of this area. Methods: We used a mathematical fitting model to express the measured data. A B time constant of a decreased bioimpedance signal during a head-up tilt was calculated for the right leg during various time intervals of tilt duration. We optimized the duration in a study protocol based on corresponding measured data and a calculated model. A group of 22 healthy volunteers (11 men and 11 women) participated in the study protocol: the protocol included a 2-minute supine position and 5-minute head-up tilt test. Results: According to the Mann-Whitney test, there were no statistical differences in the B constant between the groups of men and women. Our results showed the optimal time duration of the head-up tilt test to be about 270 s. Conclusions: Calculating the time constant for decreased bioimpedance during a head-up tilt test might lead to a simple pre-diagnostic method for performing a non-invasive evaluation of the cardiovascular system.

Název v anglickém jazyce

Measurement of blood filling in lower limbs by bioimpedance method

Popis výsledku anglicky

Background: Cardiovascular diseases are the leading causes of mortality and morbidity in modern society. The autonomic nervous systems innervate blood vessel walls and regulate contraction and wall tension. The head-up tilt test is frequently performed for evaluating sympathetic nervous system function. The filling of the lower extremities during the head-up tilt test is measured by the bioimpedance method. Increased blood volume in the area of interest increases the electrical impedance of this area. Methods: We used a mathematical fitting model to express the measured data. A B time constant of a decreased bioimpedance signal during a head-up tilt was calculated for the right leg during various time intervals of tilt duration. We optimized the duration in a study protocol based on corresponding measured data and a calculated model. A group of 22 healthy volunteers (11 men and 11 women) participated in the study protocol: the protocol included a 2-minute supine position and 5-minute head-up tilt test. Results: According to the Mann-Whitney test, there were no statistical differences in the B constant between the groups of men and women. Our results showed the optimal time duration of the head-up tilt test to be about 270 s. Conclusions: Calculating the time constant for decreased bioimpedance during a head-up tilt test might lead to a simple pre-diagnostic method for performing a non-invasive evaluation of the cardiovascular system.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

20602 - Medical laboratory technology (including laboratory samples analysis; diagnostic technologies) (Biomaterials to be 2.9 [physical characteristics of living material as related to medical implants, devices, sensors])

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BIOMEDICAL PAPERS-OLOMOUC

ISSN

1213-8118

e-ISSN

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Svazek periodika

161

Číslo periodika v rámci svazku

S1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

"S15"-"S19"

Kód UT WoS článku

000428945000003

EID výsledku v databázi Scopus

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