Impact of isotropic constitutive descriptions on the predicted peak wall stress in abdominal aortic aneurysms

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F18%3A00068708" target="_blank" >RIV/00159816:_____/18:00068708 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/18:00102966 RIV/00216305:26210/18:PU130356

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.medengphy.2018.01.002" target="_blank" >http://dx.doi.org/10.1016/j.medengphy.2018.01.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.medengphy.2018.01.002" target="_blank" >10.1016/j.medengphy.2018.01.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impact of isotropic constitutive descriptions on the predicted peak wall stress in abdominal aortic aneurysms

Popis výsledku v původním jazyce

Biomechanics-based assessment of Abdominal Aortic Aneurysm (AAA) rupture risk has gained considerable scientific and clinical momentum. However, computation of peak wall stress (PWS) using state-ofthe-art finite element models is time demanding. This study investigates which features of the constitutive description of AAA wall are decisive for achieving acceptable stress predictions in it. Influence of five different isotropic constitutive descriptions of AAA wall is tested; models reflect realistic non-linear, artificially stiff non-linear, or artificially stiff pseudo-linear constitutive descriptions of AAA wall. Influence of the AAA wall model is tested on idealized (n = 4) and patient-specific (n = 16) AAA geometries. Wall stress computations consider a (hypothetical) load-free configuration and include residual stresses homogenizing the stresses across the wall. Wall stress differences amongst the different descriptions were statistically analyzed. When the qualitatively similar non-linear response of the AAA wall with low initial stiffness and subsequent strain stiffening was taken into consideration, wall stress (and PWS) predictions did not change significantly. Keeping this non-linear feature when using an artificially stiff wall can save up to 30% of the computational time, without significant change in PWS. In contrast, a stiff pseudo-linear elastic model may underestimate the PWS and is not reliable for AAA wall stress computations.

Název v anglickém jazyce

Impact of isotropic constitutive descriptions on the predicted peak wall stress in abdominal aortic aneurysms

Popis výsledku anglicky

Biomechanics-based assessment of Abdominal Aortic Aneurysm (AAA) rupture risk has gained considerable scientific and clinical momentum. However, computation of peak wall stress (PWS) using state-ofthe-art finite element models is time demanding. This study investigates which features of the constitutive description of AAA wall are decisive for achieving acceptable stress predictions in it. Influence of five different isotropic constitutive descriptions of AAA wall is tested; models reflect realistic non-linear, artificially stiff non-linear, or artificially stiff pseudo-linear constitutive descriptions of AAA wall. Influence of the AAA wall model is tested on idealized (n = 4) and patient-specific (n = 16) AAA geometries. Wall stress computations consider a (hypothetical) load-free configuration and include residual stresses homogenizing the stresses across the wall. Wall stress differences amongst the different descriptions were statistically analyzed. When the qualitatively similar non-linear response of the AAA wall with low initial stiffness and subsequent strain stiffening was taken into consideration, wall stress (and PWS) predictions did not change significantly. Keeping this non-linear feature when using an artificially stiff wall can save up to 30% of the computational time, without significant change in PWS. In contrast, a stiff pseudo-linear elastic model may underestimate the PWS and is not reliable for AAA wall stress computations.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Medical Engineering &amp; Physics

ISSN

1350-4533

e-ISSN

—

Svazek periodika

53

Číslo periodika v rámci svazku

MAR 2018

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

49-57

Kód UT WoS článku

000429510600005

EID výsledku v databázi Scopus

2-s2.0-85041587268