Heart rate variability is associated with outcome in spontaneous intracerebral hemorrhage

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F18%3A00069025" target="_blank" >RIV/00159816:_____/18:00069025 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jcrc.2018.08.033" target="_blank" >http://dx.doi.org/10.1016/j.jcrc.2018.08.033</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jcrc.2018.08.033" target="_blank" >10.1016/j.jcrc.2018.08.033</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Heart rate variability is associated with outcome in spontaneous intracerebral hemorrhage

Popis výsledku v původním jazyce

Purpose: Autonomic imbalance as measured by heart rate variability (HRV) has been associated with poor outcome after stroke. Observations on HRV changes in intracerebral hemorrhage (ICH) are scarce. Here, we aimed to investigate HRV in ICH as compared to a control group and to explore associations with stroke severity, hemorrhage volume and outcome after ICH. Methods: We examined the autonomic modulation using frequency domain analysis of HRV during the acute phase of the ICH and in a healthy age- and hypertension-matched control group. Hematoma volume, intraventricular extension, initial stroke severity and baseline demographic, clinical parameters as well as mortality and functional outcome were included in the analysis. Results: 47 patients with ICH and 47 age- and hypertension matched controls were analyzed. ICH patients showed significantly lower total high frequency band (HF) and low frequency band (LF) powers (p = 0.01, p &lt; 0.001), higher normalized HF power (p= 0.03), and lower LF/HF ratio (p &lt; 0.001) as compared to the controls. Autonomic parameters showed associations with stroke severity (p= 0.004) and intraventricular involvement (p= 0.01) and predicted poor outcome independently (p= 0.02). Conclusions: Autonomic changes seems to be present in acute ICH and are associated with poor outcome independently. This may have future monitoring and therapeutic implications. (C) 2018 Published by Elsevier Inc.

Název v anglickém jazyce

Heart rate variability is associated with outcome in spontaneous intracerebral hemorrhage

Popis výsledku anglicky

Purpose: Autonomic imbalance as measured by heart rate variability (HRV) has been associated with poor outcome after stroke. Observations on HRV changes in intracerebral hemorrhage (ICH) are scarce. Here, we aimed to investigate HRV in ICH as compared to a control group and to explore associations with stroke severity, hemorrhage volume and outcome after ICH. Methods: We examined the autonomic modulation using frequency domain analysis of HRV during the acute phase of the ICH and in a healthy age- and hypertension-matched control group. Hematoma volume, intraventricular extension, initial stroke severity and baseline demographic, clinical parameters as well as mortality and functional outcome were included in the analysis. Results: 47 patients with ICH and 47 age- and hypertension matched controls were analyzed. ICH patients showed significantly lower total high frequency band (HF) and low frequency band (LF) powers (p = 0.01, p &lt; 0.001), higher normalized HF power (p= 0.03), and lower LF/HF ratio (p &lt; 0.001) as compared to the controls. Autonomic parameters showed associations with stroke severity (p= 0.004) and intraventricular involvement (p= 0.01) and predicted poor outcome independently (p= 0.02). Conclusions: Autonomic changes seems to be present in acute ICH and are associated with poor outcome independently. This may have future monitoring and therapeutic implications. (C) 2018 Published by Elsevier Inc.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30210 - Clinical neurology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Critical Care

ISSN

0883-9441

e-ISSN

—

Svazek periodika

48

Číslo periodika v rámci svazku

SEP 2018

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

85-89

Kód UT WoS článku

000449360800015

EID výsledku v databázi Scopus

2-s2.0-85052649654