Usefulness of Heart Rate Control in Atrial Fibrillation Patients With Obstructive Sleep Apnea

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F18%3A00069347" target="_blank" >RIV/00159816:_____/18:00069347 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.amjcard.2018.07.030" target="_blank" >http://dx.doi.org/10.1016/j.amjcard.2018.07.030</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.amjcard.2018.07.030" target="_blank" >10.1016/j.amjcard.2018.07.030</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Usefulness of Heart Rate Control in Atrial Fibrillation Patients With Obstructive Sleep Apnea

Popis výsledku v původním jazyce

In patients without atrial fibrillation and flutter (AF), obstructive sleep apnea (OSA) is associated with cyclic and often marked changes in heart rate (HR). We aimed to assess whether presence of OSA impacts optimal HR control in patients in AF. We retrospectively correlated diurnal HR patterns (recorded by 24-hour Holter monitoring) in patients with AF who independently also underwent diagnostic polysomnography. Exclusion criteria were paced rhythm or inadequate recordings from polysomnography and Holter monitoring. The relationship between the presence and severity of OSA and the mean, minimum, maximum HR, as well as pauses (&gt;2 seconds) and their diurnal variation were studied. Of the 494 studied patients (age 69 +/- 10 years; 26% women) mild-moderate OSA (apnea hypoxia index &gt;= 5 and &lt;20) was present in 171 (34%) and severe OSA (apnea hypoxia index &gt;= 20) in 254 (51 %). Mean 24-hour HR in patients with severe OSA and mild moderate OSA was similar to those without OSA (78 vs 80 vs 79 beats per minute; p = 0.39), and there was no significant difference observed in minimum and maximum HR of these groups. However, the frequency of short pauses was greater in OSA patients (p = 0.009), with a prominent nocturnal distribution. In conclusion, OSA was not associated with increased HR in patients with AF suggesting that adequate HR control was similarly achievable in patients with and without OSA. The increased frequency of nocturnal pauses in OSA patients may function as a clinical hallmark, and the timing of pauses (during sleep vs wakefulness) should be noted before making therapeutic decisions regarding HR control. (C) 2018 Published by Elsevier Inc.

Název v anglickém jazyce

Usefulness of Heart Rate Control in Atrial Fibrillation Patients With Obstructive Sleep Apnea

Popis výsledku anglicky

In patients without atrial fibrillation and flutter (AF), obstructive sleep apnea (OSA) is associated with cyclic and often marked changes in heart rate (HR). We aimed to assess whether presence of OSA impacts optimal HR control in patients in AF. We retrospectively correlated diurnal HR patterns (recorded by 24-hour Holter monitoring) in patients with AF who independently also underwent diagnostic polysomnography. Exclusion criteria were paced rhythm or inadequate recordings from polysomnography and Holter monitoring. The relationship between the presence and severity of OSA and the mean, minimum, maximum HR, as well as pauses (&gt;2 seconds) and their diurnal variation were studied. Of the 494 studied patients (age 69 +/- 10 years; 26% women) mild-moderate OSA (apnea hypoxia index &gt;= 5 and &lt;20) was present in 171 (34%) and severe OSA (apnea hypoxia index &gt;= 20) in 254 (51 %). Mean 24-hour HR in patients with severe OSA and mild moderate OSA was similar to those without OSA (78 vs 80 vs 79 beats per minute; p = 0.39), and there was no significant difference observed in minimum and maximum HR of these groups. However, the frequency of short pauses was greater in OSA patients (p = 0.009), with a prominent nocturnal distribution. In conclusion, OSA was not associated with increased HR in patients with AF suggesting that adequate HR control was similarly achievable in patients with and without OSA. The increased frequency of nocturnal pauses in OSA patients may function as a clinical hallmark, and the timing of pauses (during sleep vs wakefulness) should be noted before making therapeutic decisions regarding HR control. (C) 2018 Published by Elsevier Inc.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

<a href="/cs/project/ED1.100%2F02%2F0123" target="_blank" >ED1.100/02/0123: Fakultní nemocnice u sv. Anny v Brně - Mezinárodní centrum klinického výzkumu (FNUSA - ICRC)</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

American Journal of Cardiology

ISSN

0002-9149

e-ISSN

—

Svazek periodika

122

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

1482-1488

Kód UT WoS článku

000451363400006

EID výsledku v databázi Scopus

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