A worldwide perspective of sepsis epidemiology and survival according to age: Observational data from the ICON audit

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F19%3A00070711" target="_blank" >RIV/00159816:_____/19:00070711 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/65269705:_____/19:00070711 RIV/00179906:_____/19:10409352

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/abs/pii/S0883944118313650?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0883944118313650?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jcrc.2019.02.015" target="_blank" >10.1016/j.jcrc.2019.02.015</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A worldwide perspective of sepsis epidemiology and survival according to age: Observational data from the ICON audit

Popis výsledku v původním jazyce

Purpose: To investigate age-related differences in outcomes of critically ill patients with sepsis around the world. Methods: We performed a secondary analysis of data from the prospective ICON audit, in which all adult ( &gt;16 years ) patients admitted to participating ICUs between May 8 and 18, 2012, were included, except admissions for routine postoperative observation. For this sub-analysis, the 10,012 patients with completed age data were included. They were divided into five age groups - &lt;= 50, 51-60, 61-70, 71-80, &gt;80 years. Sepsis was defined as infection plus at least one organ failure. Results: A total of 2963 patients had sepsis, with similar proportions across the age groups (&lt;= 50 = 25.2%: 51-60 = 30.3%; 61-70 = 32.8%; 71-80 = 30.7%; &gt;80 = 30.9%). Hospital mortality increased with age and in patients &gt;80 years was almost twice that of patients &lt;= 50 years (493% vs 25.2%, p &lt; .05). The maximum rate of increase in mortality was about 0.75% per year, occurring between the ages of 71 and 77 years. In multilevel analysis, age &gt; 70 years was independently associated with increased risk of dying. Conclusions: The odds for death in ICU patients with sepsis increased with age with the maximal rate of increase occurring between the ages of 71 and 77 years. (C) 2019 Elsevier Inc. All rights reserved.

Název v anglickém jazyce

A worldwide perspective of sepsis epidemiology and survival according to age: Observational data from the ICON audit

Popis výsledku anglicky

Purpose: To investigate age-related differences in outcomes of critically ill patients with sepsis around the world. Methods: We performed a secondary analysis of data from the prospective ICON audit, in which all adult ( &gt;16 years ) patients admitted to participating ICUs between May 8 and 18, 2012, were included, except admissions for routine postoperative observation. For this sub-analysis, the 10,012 patients with completed age data were included. They were divided into five age groups - &lt;= 50, 51-60, 61-70, 71-80, &gt;80 years. Sepsis was defined as infection plus at least one organ failure. Results: A total of 2963 patients had sepsis, with similar proportions across the age groups (&lt;= 50 = 25.2%: 51-60 = 30.3%; 61-70 = 32.8%; 71-80 = 30.7%; &gt;80 = 30.9%). Hospital mortality increased with age and in patients &gt;80 years was almost twice that of patients &lt;= 50 years (493% vs 25.2%, p &lt; .05). The maximum rate of increase in mortality was about 0.75% per year, occurring between the ages of 71 and 77 years. In multilevel analysis, age &gt; 70 years was independently associated with increased risk of dying. Conclusions: The odds for death in ICU patients with sepsis increased with age with the maximal rate of increase occurring between the ages of 71 and 77 years. (C) 2019 Elsevier Inc. All rights reserved.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30221 - Critical care medicine and Emergency medicine

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Critical Care

ISSN

0883-9441

e-ISSN

—

Svazek periodika

51

Číslo periodika v rámci svazku

JUNE 2019

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

122-132

Kód UT WoS článku

000468412000023

EID výsledku v databázi Scopus

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