Non-pharmacological management of cognitive impairment in Parkinson's disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F20%3A00071909" target="_blank" >RIV/00159816:_____/20:00071909 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14740/20:00116387

Výsledek na webu

<a href="https://link.springer.com/article/10.1007%2Fs00702-019-02113-w" target="_blank" >https://link.springer.com/article/10.1007%2Fs00702-019-02113-w</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-019-02113-w" target="_blank" >10.1007/s00702-019-02113-w</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Non-pharmacological management of cognitive impairment in Parkinson's disease

Popis výsledku v původním jazyce

We evaluated the therapeutic effects of non-pharmacological interventions (cognitive training, physical activity, and non-invasive brain stimulation) on cognitive symptoms in Parkinson&apos;s disease. A comprehensive literature search for non-pharmacological intervention randomized controlled trials was performed and effect sizes were calculated for each suitable study intervention approach and cognitive domain. Despite the heterogeneity of the study results, we report level B evidence for the probable efficacy of cognitive training in improving or maintaining attention/working memory and memory domains. Level C (possible efficacy) evidence was found for specific physical training types with respect to enhancing executive functions. Non-invasive brain stimulation techniques and combinatorial approaches show preliminary but promising results. Prediction markers evaluating distinct treatment responses should be identified that would help to choose the best candidates for specific treatment strategies and cognitive symptoms. Future directions and recommendations are discussed.

Název v anglickém jazyce

Non-pharmacological management of cognitive impairment in Parkinson's disease

Popis výsledku anglicky

We evaluated the therapeutic effects of non-pharmacological interventions (cognitive training, physical activity, and non-invasive brain stimulation) on cognitive symptoms in Parkinson&apos;s disease. A comprehensive literature search for non-pharmacological intervention randomized controlled trials was performed and effect sizes were calculated for each suitable study intervention approach and cognitive domain. Despite the heterogeneity of the study results, we report level B evidence for the probable efficacy of cognitive training in improving or maintaining attention/working memory and memory domains. Level C (possible efficacy) evidence was found for specific physical training types with respect to enhancing executive functions. Non-invasive brain stimulation techniques and combinatorial approaches show preliminary but promising results. Prediction markers evaluating distinct treatment responses should be identified that would help to choose the best candidates for specific treatment strategies and cognitive symptoms. Future directions and recommendations are discussed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30210 - Clinical neurology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

—

Svazek periodika

2020

Číslo periodika v rámci svazku

MAY 2020

Stát vydavatele periodika

AT - Rakouská republika

Počet stran výsledku

12

Strana od-do

"799–820"

Kód UT WoS článku

000534796600013

EID výsledku v databázi Scopus

—