Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F20%3A00074072" target="_blank" >RIV/00159816:_____/20:00074072 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1109/EMBC44109.2020.9176326" target="_blank" >http://dx.doi.org/10.1109/EMBC44109.2020.9176326</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1109/EMBC44109.2020.9176326" target="_blank" >10.1109/EMBC44109.2020.9176326</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients
Popis výsledku v původním jazyce
Vagal Nerve Stimulation (VNS) is an option in the treatment of drug-resistant epilepsy. However, approximately a quarter of VNS subjects does not respond to the therapy. In this retrospective study, we introduce heart-rate features to distinguish VNS responders and non-responders. Standard pre-implantation measurements of 66 patients were segmented in relation to specific stimuli (open/close eyes, photic stimulation, hyperventilation, and rests between). Median interbeat intervals were found for each segment and normalized (NMRR). Five NMRRs were significant; the strongest feature achieved significance with p=0.013 and AUC=0.66. Low mutual correlation and independence on EEG signals mean that presented features could be considered as an addition for models predicting VNS response using EEG.
Název v anglickém jazyce
Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients
Popis výsledku anglicky
Vagal Nerve Stimulation (VNS) is an option in the treatment of drug-resistant epilepsy. However, approximately a quarter of VNS subjects does not respond to the therapy. In this retrospective study, we introduce heart-rate features to distinguish VNS responders and non-responders. Standard pre-implantation measurements of 66 patients were segmented in relation to specific stimuli (open/close eyes, photic stimulation, hyperventilation, and rests between). Median interbeat intervals were found for each segment and normalized (NMRR). Five NMRRs were significant; the strongest feature achieved significance with p=0.013 and AUC=0.66. Low mutual correlation and independence on EEG signals mean that presented features could be considered as an addition for models predicting VNS response using EEG.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
—
OECD FORD obor
30100 - Basic medicine
Návaznosti výsledku
Projekt
<a href="/cs/project/NV19-04-00343" target="_blank" >NV19-04-00343: Predikce Efektu Stimulace u pacientů s Epilepsií (PRESEnCE)</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2020
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů