Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F20%3A00535662" target="_blank" >RIV/68081731:_____/20:00535662 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/20:00118651

Výsledek na webu

<a href="https://ieeexplore.ieee.org/document/9176326" target="_blank" >https://ieeexplore.ieee.org/document/9176326</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/EMBC44109.2020.9176326" target="_blank" >10.1109/EMBC44109.2020.9176326</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients

Popis výsledku v původním jazyce

Vagal Nerve Stimulation (VNS) is an option in the treatment of drug-resistant epilepsy. However, approximately a quarter of VNS subjects does not respond to the therapy. In this retrospective study, we introduce heart-rate features to distinguish VNS responders and non-responders. Standard pre-implantation measurements of 66 patients were segmented in relation to specific stimuli (open/close eyes, photic stimulation, hyperventilation, and rests between). Median interbeat intervals were found for each segment and normalized (NMRR). Five NMRRs were significant, the strongest feature achieved significance with p=0.013 and AUC=0.66. Low mutual correlation and independence on EEG signals mean that presented features could be considered as an addition for models predicting VNS response using EEG.

Název v anglickém jazyce

Response to Vagal Stimulation by Heart-rate Features in Drug-resistant Epileptic Patients

Popis výsledku anglicky

Vagal Nerve Stimulation (VNS) is an option in the treatment of drug-resistant epilepsy. However, approximately a quarter of VNS subjects does not respond to the therapy. In this retrospective study, we introduce heart-rate features to distinguish VNS responders and non-responders. Standard pre-implantation measurements of 66 patients were segmented in relation to specific stimuli (open/close eyes, photic stimulation, hyperventilation, and rests between). Median interbeat intervals were found for each segment and normalized (NMRR). Five NMRRs were significant, the strongest feature achieved significance with p=0.013 and AUC=0.66. Low mutual correlation and independence on EEG signals mean that presented features could be considered as an addition for models predicting VNS response using EEG.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

<a href="/cs/project/NV19-04-00343" target="_blank" >NV19-04-00343: Predikce Efektu Stimulace u pacientů s Epilepsií (PRESEnCE)</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). Proceedings

ISBN

978-172811990-8

ISSN

1557-170X

e-ISSN

—

Počet stran výsledku

4

Strana od-do

46-49

Název nakladatele

IEEE

Místo vydání

New York

Místo konání akce

Montreal

Datum konání akce

20. 7. 2020

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000621592200012