Can different type of the pressure ulcers debridement affect oxidative stress parameters?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F22%3A00076389" target="_blank" >RIV/00159816:_____/22:00076389 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/65269705:_____/22:00076389 RIV/00216224:14110/22:00129732

Výsledek na webu

<a href="https://www.prolekare.cz/casopisy/ceska-slovenska-neurologie/2022-supplementum-1-1/ovlivni-typ-nekrektomie-dekubitu-parametry-oxidativniho-stresu-130720/download?hl=cs" target="_blank" >https://www.prolekare.cz/casopisy/ceska-slovenska-neurologie/2022-supplementum-1-1/ovlivni-typ-nekrektomie-dekubitu-parametry-oxidativniho-stresu-130720/download?hl=cs</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.48095/cccsnn2022S34" target="_blank" >10.48095/cccsnn2022S34</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Can different type of the pressure ulcers debridement affect oxidative stress parameters?

Popis výsledku v původním jazyce

Wound debridement is one of the crucial steps in wound bed preparation for surgical closure. Various debridement forms and tools can be employed. Aim: The prospective case series study aimed to compare the impact of two diff erent types of debridement on oxidative stress parameters. Material and methods: This study included fi ve patients with pressure ulcers of deep category various localisation. The wound was divided into halves. In one, the sharp debridement was performed, in the second Hydrosurgery Versajet(R) debridement was accomplished. Tissue, blood and urine samples were collected on days 0 and 7 after the surgery. Histopathological evaluation in tissue samples was performed. Oxidative stress parameters in plasma and urine were evaluated. Results: Diff erences in quality and quantity of granulation tissue between two types of debridement were found. An insignifi cant decrease of oxidative stress markers in blood plasma and urine 7 days after surgery were observed. Conclusions: Preliminary and pilot results suggest that the wound healing process is closely associated with markers of oxidative stress that are measurable in blood plasma and urine. These could be indicative of the healing process. A nonsignificant decrease was observed for all oxidative stress parameters on day 7 after the surgery. The pilot study will be followed by a detailed molecular bio logical analysis of tissue samples.

Název v anglickém jazyce

Can different type of the pressure ulcers debridement affect oxidative stress parameters?

Popis výsledku anglicky

Wound debridement is one of the crucial steps in wound bed preparation for surgical closure. Various debridement forms and tools can be employed. Aim: The prospective case series study aimed to compare the impact of two diff erent types of debridement on oxidative stress parameters. Material and methods: This study included fi ve patients with pressure ulcers of deep category various localisation. The wound was divided into halves. In one, the sharp debridement was performed, in the second Hydrosurgery Versajet(R) debridement was accomplished. Tissue, blood and urine samples were collected on days 0 and 7 after the surgery. Histopathological evaluation in tissue samples was performed. Oxidative stress parameters in plasma and urine were evaluated. Results: Diff erences in quality and quantity of granulation tissue between two types of debridement were found. An insignifi cant decrease of oxidative stress markers in blood plasma and urine 7 days after surgery were observed. Conclusions: Preliminary and pilot results suggest that the wound healing process is closely associated with markers of oxidative stress that are measurable in blood plasma and urine. These could be indicative of the healing process. A nonsignificant decrease was observed for all oxidative stress parameters on day 7 after the surgery. The pilot study will be followed by a detailed molecular bio logical analysis of tissue samples.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30212 - Surgery

Projekt

<a href="/cs/project/NU21-09-00541" target="_blank" >NU21-09-00541: Role oxidativního stresu při hojení dekubitů u pacientů s míšní lézí</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Česká a slovenská neurologie a neurochirurgie

ISSN

1210-7859

e-ISSN

1802-4041

Svazek periodika

85

Číslo periodika v rámci svazku

Suppl. 1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

4

Strana od-do

"S34"-"S37"

Kód UT WoS článku

000910094000001

EID výsledku v databázi Scopus

2-s2.0-85132170573