CT-derived adipose tissue characteristics and TAVI all-cause mortality and complications: a systematic review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00159816%3A_____%2F25%3A00082408" target="_blank" >RIV/00159816:_____/25:00082408 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/25:00141060 RIV/61988987:17110/25:A2603DD4 RIV/00216208:11120/25:43928380 RIV/61989100:27240/25:10257798

Výsledek na webu

<a href="https://link.springer.com/article/10.1186/s40001-025-02587-3" target="_blank" >https://link.springer.com/article/10.1186/s40001-025-02587-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s40001-025-02587-3" target="_blank" >10.1186/s40001-025-02587-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

CT-derived adipose tissue characteristics and TAVI all-cause mortality and complications: a systematic review

Popis výsledku v původním jazyce

Transcatheter Aortic Valve Implantation (TAVI) has revolutionized severe aortic stenosis treatment, but risk stratification remains challenging. This systematic review examined the association between computed tomography (CT)-derived adipose tissue parameters and TAVI outcomes. We searched major databases for studies on visceral (VAT), subcutaneous (SAT), and intramuscular (IMAT) adipose tissue parameters and post-TAVI outcomes. Fourteen studies (9692 patients) were included. Higher SAT area/volume was consistently associated with better survival (5 studies, HR range: 0.83-2.77, p &lt; 0.05). Lower SAT and VAT density also correlated with better survival (5 and 4 studies, respectively, HR range: 1.31-1.46, p &lt; 0.05). VAT area showed mixed results. A VAT:SAT ratio &lt; 1 was associated with better cardiovascular outcomes in one study. Lower IMAT index correlated with shorter hospital stays in a single study. This review reveals complex relationships between adipose tissue parameters and TAVI outcomes. Lower adipose tissue density and higher subcutaneous adiposity were most consistently associated with better outcomes. These findings suggest that detailed analysis of adipose tissue characteristics may enhance risk stratification in TAVI candidates.

Název v anglickém jazyce

CT-derived adipose tissue characteristics and TAVI all-cause mortality and complications: a systematic review

Popis výsledku anglicky

Transcatheter Aortic Valve Implantation (TAVI) has revolutionized severe aortic stenosis treatment, but risk stratification remains challenging. This systematic review examined the association between computed tomography (CT)-derived adipose tissue parameters and TAVI outcomes. We searched major databases for studies on visceral (VAT), subcutaneous (SAT), and intramuscular (IMAT) adipose tissue parameters and post-TAVI outcomes. Fourteen studies (9692 patients) were included. Higher SAT area/volume was consistently associated with better survival (5 studies, HR range: 0.83-2.77, p &lt; 0.05). Lower SAT and VAT density also correlated with better survival (5 and 4 studies, respectively, HR range: 1.31-1.46, p &lt; 0.05). VAT area showed mixed results. A VAT:SAT ratio &lt; 1 was associated with better cardiovascular outcomes in one study. Lower IMAT index correlated with shorter hospital stays in a single study. This review reveals complex relationships between adipose tissue parameters and TAVI outcomes. Lower adipose tissue density and higher subcutaneous adiposity were most consistently associated with better outcomes. These findings suggest that detailed analysis of adipose tissue characteristics may enhance risk stratification in TAVI candidates.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Medical Research

ISSN

0949-2321

e-ISSN

2047-783X

Svazek periodika

30

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

13

Strana od-do

nestránkováno

Kód UT WoS článku

001473615600001

EID výsledku v databázi Scopus

—