Final publishable report from 18HLT04 UHDpulse

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00177016%3A_____%2F23%3AN0000077" target="_blank" >RIV/00177016:_____/23:N0000077 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Final publishable report from 18HLT04 UHDpulse

Popis výsledku v původním jazyce

Příspěvek ČMI: plnění pracovních povinností daných protokolem projektu In vivo radiobiological experiments have shown that irradiation with electron beams and ultra-high doses per pulse leads to a dramatic reduction of adverse side effects. However, pulses with dose rates higher than conventional radiotherapy present significant metrological challenges. Most of the dosimetry detection systems used in electron and proton therapy beam monitoring, quality assurance, and commissioning had shown saturation effects or were unable to detect the entire radiation dose in such a short time of ultra-high dose delivery. The project investigated several technological challenges and state-of-the-art ideas for detector development, calibrations, and a metrological framework for traceable absorbed dose measurements. As a result, this project established metrology standards, traceability methods, and the development of new detection systems for beam monitoring and field characterisation. This includes i) a robust metrological framework, establishing SI-traceable primary and secondary reference standards and validated methods for dosimetry measurements in particle beams with ultra-high pulse dose rates, ii) characterised the response of available detector systems, iii) developed traceable and validated methods for relative dosimetry and characterisation of stray radiation outside the primary pulsed particle beams, ensuring safer and more effective treatments, and iv) provided essential input data for Codes of Practice for absolute dose measurements. Overall, the project's achievements significantly enhanced the accuracy and reliability of dosimetry in ultra-high dose rate treatment techniques, empowering medical professionals and researchers to deliver more effective and safer radiotherapy. The project's outcomes have directly addressed the user's needs, enabling improved treatment, quality assurance, and commissioning in pre-clinical, clinical and research laboratories

Název v anglickém jazyce

Final publishable report from 18HLT04 UHDpulse

Popis výsledku anglicky

Příspěvek ČMI: plnění pracovních povinností daných protokolem projektu In vivo radiobiological experiments have shown that irradiation with electron beams and ultra-high doses per pulse leads to a dramatic reduction of adverse side effects. However, pulses with dose rates higher than conventional radiotherapy present significant metrological challenges. Most of the dosimetry detection systems used in electron and proton therapy beam monitoring, quality assurance, and commissioning had shown saturation effects or were unable to detect the entire radiation dose in such a short time of ultra-high dose delivery. The project investigated several technological challenges and state-of-the-art ideas for detector development, calibrations, and a metrological framework for traceable absorbed dose measurements. As a result, this project established metrology standards, traceability methods, and the development of new detection systems for beam monitoring and field characterisation. This includes i) a robust metrological framework, establishing SI-traceable primary and secondary reference standards and validated methods for dosimetry measurements in particle beams with ultra-high pulse dose rates, ii) characterised the response of available detector systems, iii) developed traceable and validated methods for relative dosimetry and characterisation of stray radiation outside the primary pulsed particle beams, ensuring safer and more effective treatments, and iv) provided essential input data for Codes of Practice for absolute dose measurements. Overall, the project's achievements significantly enhanced the accuracy and reliability of dosimetry in ultra-high dose rate treatment techniques, empowering medical professionals and researchers to deliver more effective and safer radiotherapy. The project's outcomes have directly addressed the user's needs, enabling improved treatment, quality assurance, and commissioning in pre-clinical, clinical and research laboratories

Druh

V_souhrn - Souhrnná výzkumná zpráva

CEP obor

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OECD FORD obor

10304 - Nuclear physics

Projekt

<a href="/cs/project/8B19001" target="_blank" >8B19001: Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Počet stran výsledku

19

Místo vydání

PTB Branschweig, Německo

Název nakladatele resp. objednatele

EURAMET

Verze

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