Haemorheopheresis could block the progression of the dry form of age-related macular degeneration with soft drusen to the neovascular form

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F11%3A10080213" target="_blank" >RIV/00179906:_____/11:10080213 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/11:10080213

Výsledek na webu

<a href="http://onlinelibrary.wiley.com/doi/10.1111/j.1755-3768.2009.01710.x/pdf" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1111/j.1755-3768.2009.01710.x/pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1755-3768.2009.01710.x" target="_blank" >10.1111/j.1755-3768.2009.01710.x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Haemorheopheresis could block the progression of the dry form of age-related macular degeneration with soft drusen to the neovascular form

Popis výsledku v původním jazyce

The aim of the study was the evaluation of the influence of haemorheopheresis on soft-drusen maculopathy. We investigated 29 eyes (16 patients) and randomized 25 eyes (16 controls) with soft-drusen maculopathy. Each patient received 8 series of haemorheophereses (cascade filtration of 1.5 plasma volume within 10 weeks. After the procedures, there was a substantial reduction in rheologically active substances, plasma and blood viscosity. At the 1.5-year follow-up, we noticed soft drusen absorption; reattachment of drusenoid RPED and stabilization or improvement of visual acuity occurred in 72% of patients in comparison to only 39% of patients in the control group. Haemorheopheresis seems to be capable of changing the activity of promoters of the natural course of soft-drusen maculopathy, its development and progression. Visual acuity and electrical activity of the retina can be stabilized or even improved. The therapy has been shown to be effective and safe.

Název v anglickém jazyce

Haemorheopheresis could block the progression of the dry form of age-related macular degeneration with soft drusen to the neovascular form

Popis výsledku anglicky

The aim of the study was the evaluation of the influence of haemorheopheresis on soft-drusen maculopathy. We investigated 29 eyes (16 patients) and randomized 25 eyes (16 controls) with soft-drusen maculopathy. Each patient received 8 series of haemorheophereses (cascade filtration of 1.5 plasma volume within 10 weeks. After the procedures, there was a substantial reduction in rheologically active substances, plasma and blood viscosity. At the 1.5-year follow-up, we noticed soft drusen absorption; reattachment of drusenoid RPED and stabilization or improvement of visual acuity occurred in 72% of patients in comparison to only 39% of patients in the control group. Haemorheopheresis seems to be capable of changing the activity of promoters of the natural course of soft-drusen maculopathy, its development and progression. Visual acuity and electrical activity of the retina can be stabilized or even improved. The therapy has been shown to be effective and safe.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30208 - Dentistry, oral surgery and medicine

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Ophthalmologica

ISSN

1755-375X

e-ISSN

—

Svazek periodika

89

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

DK - Dánské království

Počet stran výsledku

9

Strana od-do

463-471

Kód UT WoS článku

000292742800033

EID výsledku v databázi Scopus

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