Cholesterol metabolism in acute upper gastrointestinal bleeding, preliminary observations

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F12%3A10128488" target="_blank" >RIV/00179906:_____/12:10128488 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61988987:17110/12:A13016OC RIV/00216208:11150/12:10128488 RIV/00843989:_____/12:00102803

Výsledek na webu

<a href="http://link.springer.com/article/10.1007%2Fs00508-012-0292-0" target="_blank" >http://link.springer.com/article/10.1007%2Fs00508-012-0292-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00508-012-0292-0" target="_blank" >10.1007/s00508-012-0292-0</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cholesterol metabolism in acute upper gastrointestinal bleeding, preliminary observations

Popis výsledku v původním jazyce

Hypocholesterolemia is commonly found in critically ill patients; however, the aetiology of this condition remains unclear. Several clinical studies refer to the possible negative impact of haemodilution on cholesterol (CH) metabolism in acute medical conditions. The aim of this study was to examine the serum CH profile (total CH, LDL and HDL CH) during acute gastrointestinal bleeding which is a life-threatening condition characterised by alterations in lipid metabolism. Serum non-CH sterols (lathosterol, squalene, sitosterol and campesterol) concentrations os markers of CH synthesis and CH absorption were measured at the same time. Twenty-four patients with acute upper gastrointestinal bleeding (UGIB) were measured for these parameters over a 6-day period. The control group was 100 healthy blood donors. We found lower plasma levels of total CH (p<0,001) and LDL CH (p<0,05) in patients with UGIB than in the control group. The decreased HDL CH plasma levels in patients were not statisti

Název v anglickém jazyce

Cholesterol metabolism in acute upper gastrointestinal bleeding, preliminary observations

Popis výsledku anglicky

Hypocholesterolemia is commonly found in critically ill patients; however, the aetiology of this condition remains unclear. Several clinical studies refer to the possible negative impact of haemodilution on cholesterol (CH) metabolism in acute medical conditions. The aim of this study was to examine the serum CH profile (total CH, LDL and HDL CH) during acute gastrointestinal bleeding which is a life-threatening condition characterised by alterations in lipid metabolism. Serum non-CH sterols (lathosterol, squalene, sitosterol and campesterol) concentrations os markers of CH synthesis and CH absorption were measured at the same time. Twenty-four patients with acute upper gastrointestinal bleeding (UGIB) were measured for these parameters over a 6-day period. The control group was 100 healthy blood donors. We found lower plasma levels of total CH (p<0,001) and LDL CH (p<0,05) in patients with UGIB than in the control group. The decreased HDL CH plasma levels in patients were not statisti

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Wiener Klinische Wochenschrift

ISSN

0043-5325

e-ISSN

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Svazek periodika

124

Číslo periodika v rámci svazku

23-24

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

7

Strana od-do

815-821

Kód UT WoS článku

000312731900002

EID výsledku v databázi Scopus

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