D-dimer levels and 90-day outcome in patients with acute pulmonary embolism with or without cancer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10282892" target="_blank" >RIV/00179906:_____/14:10282892 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/14:10282892

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.thromres.2013.12.044" target="_blank" >http://dx.doi.org/10.1016/j.thromres.2013.12.044</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.thromres.2013.12.044" target="_blank" >10.1016/j.thromres.2013.12.044</a>

Jazyk výsledku

angličtina

Název v původním jazyce

D-dimer levels and 90-day outcome in patients with acute pulmonary embolism with or without cancer

Popis výsledku v původním jazyce

Background: The prognostic value of D-dimer testing in patients with acute pulmonary embolism (PE) has not been thoroughly studied. Methods: We used the RIETE Registry data to assess the 90-day prognostic value of increased IL Test D-dimer (R) levels atbaseline in patients with PE, according to the presence or absence of cancer. Results: As of May 2013, 3,283 patients with acute PE underwent D-dimer testing using IL Test D-dimer (R). Among 2,588 patients without cancer, those with D-dimer levels in thehighest quartile had a higher rate of fatal PE (2.6% vs. 0.9%; p = 0.002), fatal bleeding (1.1% vs. 0.3%; p = 0.017) and all-cause death (9.1% vs. 4.4%; p < 0.001) at 90 days compared with those with levels in the lowest quartiles. Among 695 patients with cancer, those with levels in the highest quartile had a similar rate of fatal PE or fatal bleeding but higher mortality (35% vs. 24%; p < 0.01). On multivariate analysis, non-cancer patients with D-dimer levels in the highest quartile

Název v anglickém jazyce

D-dimer levels and 90-day outcome in patients with acute pulmonary embolism with or without cancer

Popis výsledku anglicky

Background: The prognostic value of D-dimer testing in patients with acute pulmonary embolism (PE) has not been thoroughly studied. Methods: We used the RIETE Registry data to assess the 90-day prognostic value of increased IL Test D-dimer (R) levels atbaseline in patients with PE, according to the presence or absence of cancer. Results: As of May 2013, 3,283 patients with acute PE underwent D-dimer testing using IL Test D-dimer (R). Among 2,588 patients without cancer, those with D-dimer levels in thehighest quartile had a higher rate of fatal PE (2.6% vs. 0.9%; p = 0.002), fatal bleeding (1.1% vs. 0.3%; p = 0.017) and all-cause death (9.1% vs. 4.4%; p < 0.001) at 90 days compared with those with levels in the lowest quartiles. Among 695 patients with cancer, those with levels in the highest quartile had a similar rate of fatal PE or fatal bleeding but higher mortality (35% vs. 24%; p < 0.01). On multivariate analysis, non-cancer patients with D-dimer levels in the highest quartile

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Thrombosis Research

ISSN

0049-3848

e-ISSN

—

Svazek periodika

133

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

384-389

Kód UT WoS článku

000331540400016

EID výsledku v databázi Scopus

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