Multipotent mesenchymal stromal cells in otorhinolaryngology

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F14%3A10283783" target="_blank" >RIV/00179906:_____/14:10283783 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378041:_____/14:00432940 RIV/00216208:11150/14:10283783

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0306987714001352" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0306987714001352</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mehy.2014.03.022" target="_blank" >10.1016/j.mehy.2014.03.022</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Multipotent mesenchymal stromal cells in otorhinolaryngology

Popis výsledku v původním jazyce

Multipotent mesenchymal stromal cells (MSCs) are primitive cells capable of restoring damaged mesenchyme and with the ability to differentiate into mature cells of bone, cartilage, muscle, fat, nerve or fibrous tissues. MSCs are therefore good candidatesfor applications in regenerative medicine and cell based therapy. They regenerate through self-renewal, differentiational capacity, immune modulation and secretion of bioactive molecules. Authors present a review of MSCs applications in otorhinolaryngology. The major interest is focused on phonosurgery, sensorineural deafness and reconstruction of large tissue defects with bone, cartilage or soft tissue replacement. Current evidence of MSCs treatment efficacy in otorhinolaryngology is based on animal models. The true impact on clinical treatment will not be known until clinical studies prove functional outcomes in human medicine.

Název v anglickém jazyce

Multipotent mesenchymal stromal cells in otorhinolaryngology

Popis výsledku anglicky

Multipotent mesenchymal stromal cells (MSCs) are primitive cells capable of restoring damaged mesenchyme and with the ability to differentiate into mature cells of bone, cartilage, muscle, fat, nerve or fibrous tissues. MSCs are therefore good candidatesfor applications in regenerative medicine and cell based therapy. They regenerate through self-renewal, differentiational capacity, immune modulation and secretion of bioactive molecules. Authors present a review of MSCs applications in otorhinolaryngology. The major interest is focused on phonosurgery, sensorineural deafness and reconstruction of large tissue defects with bone, cartilage or soft tissue replacement. Current evidence of MSCs treatment efficacy in otorhinolaryngology is based on animal models. The true impact on clinical treatment will not be known until clinical studies prove functional outcomes in human medicine.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FF - ORL, oftalmologie, stomatologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Medical Hypotheses

ISSN

0306-9877

e-ISSN

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Svazek periodika

82

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

769-773

Kód UT WoS článku

000336704200028

EID výsledku v databázi Scopus

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