Recent advances in the determination of tocopherols in biological fluids: from sample pretreatment and liquid chromatography to clinical studies
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F16%3A10321341" target="_blank" >RIV/00179906:_____/16:10321341 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11160/16:10321341 RIV/61989592:15110/16:33160416
Výsledek na webu
<a href="http://link.springer.com/article/10.1007/s00216-015-9214-0/fulltext.html" target="_blank" >http://link.springer.com/article/10.1007/s00216-015-9214-0/fulltext.html</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00216-015-9214-0" target="_blank" >10.1007/s00216-015-9214-0</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Recent advances in the determination of tocopherols in biological fluids: from sample pretreatment and liquid chromatography to clinical studies
Popis výsledku v původním jazyce
Vitamin E comprises eight related compounds: alpha-, beta-, gamma-, delta-tocopherols and alpha-, beta-, gamma-, delta-tocotrienols. In the past, alpha-tocopherol has been the isomer that was studied most, and its anti-inflammatory and anti-proliferative effects have been described. Therefore, many prevention trials have investigated the effect of alpha-tocopherol on human health. Current research studies have also defined the important roles of other tocopherols, such as anti-inflammatory, anti-proliferative and cancer preventative effects. Knowledge of the individual tocopherols could help to understand their roles in various metabolic pathways. This review summarizes the recent trends in sample pretreatment, liquid chromatography and selected applications of the determination of tocopherols in various biological materials. The relationship between tocopherol isomers and serious diseases is also described.
Název v anglickém jazyce
Recent advances in the determination of tocopherols in biological fluids: from sample pretreatment and liquid chromatography to clinical studies
Popis výsledku anglicky
Vitamin E comprises eight related compounds: alpha-, beta-, gamma-, delta-tocopherols and alpha-, beta-, gamma-, delta-tocotrienols. In the past, alpha-tocopherol has been the isomer that was studied most, and its anti-inflammatory and anti-proliferative effects have been described. Therefore, many prevention trials have investigated the effect of alpha-tocopherol on human health. Current research studies have also defined the important roles of other tocopherols, such as anti-inflammatory, anti-proliferative and cancer preventative effects. Knowledge of the individual tocopherols could help to understand their roles in various metabolic pathways. This review summarizes the recent trends in sample pretreatment, liquid chromatography and selected applications of the determination of tocopherols in various biological materials. The relationship between tocopherol isomers and serious diseases is also described.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CB - Analytická chemie, separace
OECD FORD obor
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Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2016
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Analytical and Bioanalytical Chemistry
ISSN
1618-2642
e-ISSN
—
Svazek periodika
408
Číslo periodika v rámci svazku
10
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
18
Strana od-do
2407-2424
Kód UT WoS článku
000373791400002
EID výsledku v databázi Scopus
2-s2.0-84954328326