Sipping as a Nutritional Supplement in Ambulatory Palliative Oncology Care: A Pilot Study with Noninvasive Methods

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00179906%3A_____%2F23%3A10473489" target="_blank" >RIV/00179906:_____/23:10473489 - isvavai.cz</a>

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=0~4ysw4y_m" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=0~4ysw4y_m</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1089/jmf.2023.0033" target="_blank" >10.1089/jmf.2023.0033</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Sipping as a Nutritional Supplement in Ambulatory Palliative Oncology Care: A Pilot Study with Noninvasive Methods

Popis výsledku v původním jazyce

Objective: The implementation of nutritional support is a basic need of patients in palliative oncological care. This pilot study optimized the use of sipping to improve the nutritional status of cancer patients in palliative care. Materials and Method: The pilot study included 63 patients, 61.3 years of age on average (range: 32-82 years of age). The patients were assigned to either group A (no nutritional support n = 39 patients) or group B (sipping as nutritional support n = 24 patients). The patients were evaluated through by noninvasive methods: body weight, waist and arm circumference, and triceps skinfold, bioimpedance analysis, and dynamometry. Quality of life was assessed through modified questionnaires. Results: In contrast with group A, group B did not have a significant weight loss, that is, A: 81.9 +/- 15.8-80.5 +/- 15.8 kg (P = .028) and B: 73.9 +/- 14.9-73 +/- 16 kg. Body mass index A: 29 +/- 5-28.5 +/- 5 kg/m(2) (P = .007) and B: 25.3 +/- 4.7-25 +/- 4.9 kg/m(2) (P = .614). Waist circumference A: 93.5 +/- 15.1-92.5 +/- 14.8 cm (P = .008) and B: 80.1 +/- 13.2-80.6 +/- 12.3 cm (P = .234). Triceps skinfold A: 12.3 +/- 7.2-11 +/- 6.7 mm (P = .001) and B: 8.2 +/- 6.1-7.9 +/- 5.7 mm (P = .207). Fat free mass A: 54.8 +/- 11.5-52.8 +/- 11.6 kg (P = .018) and B: 54.7 +/- 10.9-52.8 +/- 11.5 kg (P = .207). Significantly lower dynamometer values were recorded in both groups; A: 25.6 +/- 10.4-23.1 +/- 10.3 kg (P = .010) and B: 27.4 +/- 9.9-24.3 +/- 9.1 kg (P = .009). In contrast to group B, the patients in group A showed slight variations in their health status, thus decreasing their scores into the significance limit (P = .072). Conclusion: Our results suggest that providing nutritional support in the form of sipping (similar to 12 g proteins, 300 kcal) on a daily basis prevents the loss of active tissue mass in palliative oncology patients. Based on these results, we recommend the inclusion of this simple nutritional support to prevent malnutrition in cancer patients in palliative care. The clinical study was registered by the internal ethics committee under the heading of its approval - Institutional Ethics Committee of the Hradec Kr &amp; aacute;lov &amp; eacute; Faculty Hospital, number 201311S2OP.

Název v anglickém jazyce

Sipping as a Nutritional Supplement in Ambulatory Palliative Oncology Care: A Pilot Study with Noninvasive Methods

Popis výsledku anglicky

Objective: The implementation of nutritional support is a basic need of patients in palliative oncological care. This pilot study optimized the use of sipping to improve the nutritional status of cancer patients in palliative care. Materials and Method: The pilot study included 63 patients, 61.3 years of age on average (range: 32-82 years of age). The patients were assigned to either group A (no nutritional support n = 39 patients) or group B (sipping as nutritional support n = 24 patients). The patients were evaluated through by noninvasive methods: body weight, waist and arm circumference, and triceps skinfold, bioimpedance analysis, and dynamometry. Quality of life was assessed through modified questionnaires. Results: In contrast with group A, group B did not have a significant weight loss, that is, A: 81.9 +/- 15.8-80.5 +/- 15.8 kg (P = .028) and B: 73.9 +/- 14.9-73 +/- 16 kg. Body mass index A: 29 +/- 5-28.5 +/- 5 kg/m(2) (P = .007) and B: 25.3 +/- 4.7-25 +/- 4.9 kg/m(2) (P = .614). Waist circumference A: 93.5 +/- 15.1-92.5 +/- 14.8 cm (P = .008) and B: 80.1 +/- 13.2-80.6 +/- 12.3 cm (P = .234). Triceps skinfold A: 12.3 +/- 7.2-11 +/- 6.7 mm (P = .001) and B: 8.2 +/- 6.1-7.9 +/- 5.7 mm (P = .207). Fat free mass A: 54.8 +/- 11.5-52.8 +/- 11.6 kg (P = .018) and B: 54.7 +/- 10.9-52.8 +/- 11.5 kg (P = .207). Significantly lower dynamometer values were recorded in both groups; A: 25.6 +/- 10.4-23.1 +/- 10.3 kg (P = .010) and B: 27.4 +/- 9.9-24.3 +/- 9.1 kg (P = .009). In contrast to group B, the patients in group A showed slight variations in their health status, thus decreasing their scores into the significance limit (P = .072). Conclusion: Our results suggest that providing nutritional support in the form of sipping (similar to 12 g proteins, 300 kcal) on a daily basis prevents the loss of active tissue mass in palliative oncology patients. Based on these results, we recommend the inclusion of this simple nutritional support to prevent malnutrition in cancer patients in palliative care. The clinical study was registered by the internal ethics committee under the heading of its approval - Institutional Ethics Committee of the Hradec Kr &amp; aacute;lov &amp; eacute; Faculty Hospital, number 201311S2OP.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30204 - Oncology

Projekt

<a href="/cs/project/NU20-09-00045" target="_blank" >NU20-09-00045: Analýza faktorů ovlivňujících kvalitu života u nemocných v paliativní onkologické péči - personalizovaný přístup v specializované ambulanci.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Medicinal Food

ISSN

1096-620X

e-ISSN

1557-7600

Svazek periodika

26

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

943-950

Kód UT WoS článku

001117623700009

EID výsledku v databázi Scopus

2-s2.0-85174548840