A Pooled analysis of alcohol consumption and risk of multiple myeloma in the International Multiple Myeloma Consortium

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F13%3A%230000433" target="_blank" >RIV/00209805:_____/13:#0000433 - isvavai.cz</a>

Výsledek na webu

<a href="http://cebp.aacrjournals.org/content/22/9/1620.full.pdf+html" target="_blank" >http://cebp.aacrjournals.org/content/22/9/1620.full.pdf+html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1158/1055-9965.EPI-13-0334" target="_blank" >10.1158/1055-9965.EPI-13-0334</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A Pooled analysis of alcohol consumption and risk of multiple myeloma in the International Multiple Myeloma Consortium

Popis výsledku v původním jazyce

Recent findings suggest that alcohol consumption may reduce risk of multiple myeloma. To better understand this relationship, we conducted an analysis of six case-control studies participating in the International Multiple Myeloma Consortium (1,567 cases, 7,296 controls). Summary ORs and 95% confidence intervals (CI) relating different measures of alcohol consumption and multiple myeloma risk were computed by unconditional logistic regression with adjustment for age, race, and study center. Cases were significantly less likely than controls to report ever drinking alcohol (men: OR 1/4 0.72; 95% CI, 0.59-0.89; women: OR 1/4 0.81; 95% CI, 0.68-0.95). The inverse association with multiple myeloma was stronger when comparing current to never drinkers (men:OR 1/4 0.57; 95% CI, 0.45-0.72; women:OR 1/4 0.55; 95% CI, 0.45-0.68), but null among former drinkers. We did not observe an exposure-response relationship with increasing alcohol frequency, duration, or cumulative lifetime consumption. A

Název v anglickém jazyce

A Pooled analysis of alcohol consumption and risk of multiple myeloma in the International Multiple Myeloma Consortium

Popis výsledku anglicky

Recent findings suggest that alcohol consumption may reduce risk of multiple myeloma. To better understand this relationship, we conducted an analysis of six case-control studies participating in the International Multiple Myeloma Consortium (1,567 cases, 7,296 controls). Summary ORs and 95% confidence intervals (CI) relating different measures of alcohol consumption and multiple myeloma risk were computed by unconditional logistic regression with adjustment for age, race, and study center. Cases were significantly less likely than controls to report ever drinking alcohol (men: OR 1/4 0.72; 95% CI, 0.59-0.89; women: OR 1/4 0.81; 95% CI, 0.68-0.95). The inverse association with multiple myeloma was stronger when comparing current to never drinkers (men:OR 1/4 0.57; 95% CI, 0.45-0.72; women:OR 1/4 0.55; 95% CI, 0.45-0.68), but null among former drinkers. We did not observe an exposure-response relationship with increasing alcohol frequency, duration, or cumulative lifetime consumption. A

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

<a href="/cs/project/ED2.1.00%2F03.0101" target="_blank" >ED2.1.00/03.0101: Regionální centrum aplikované molekulární onkologie (RECAMO)</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cancer Epidemiology, Biomarkers and Prevention

ISSN

1055-9965

e-ISSN

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Svazek periodika

22

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

1620-1627

Kód UT WoS článku

000324674500015

EID výsledku v databázi Scopus

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