Metastases of a Breast Cancer to Skull Base

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F18%3A00078152" target="_blank" >RIV/00209805:_____/18:00078152 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.linkos.cz/casopis-klinicka-onkologie/2018-08-15-4/metastazy-karcinomu-prsu-do-baze-lebni/" target="_blank" >https://www.linkos.cz/casopis-klinicka-onkologie/2018-08-15-4/metastazy-karcinomu-prsu-do-baze-lebni/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14735/amko2018293" target="_blank" >10.14735/amko2018293</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Metastases of a Breast Cancer to Skull Base

Popis výsledku v původním jazyce

Background: Breast cancer (BC) is a frequent malignant disease which tends to develop distant metastases, but only very rarely in the head and neck region. Case report: We present two case reports of patients with metastases of invasive BC in this area. They are of different clinical manifestation with different time relation to the primary tumor and different symptomatology. In the case of the first patient, a few years without evidence of malignant disease after treatment of primary tumor in complete remission. In the case of the second patient, as the first symptom of undiagnosed disease. Metastases were clinically observed in the skull base and maxillarysinus, manifest ing neurologically with foramen jugulare syndrome and orbital symptoms, resp. In both cases, correlations between histological and clinical fi ndings were essential for dia gnosis. Palliative multimodal treatment was then employed. Conclusion: Metastases of BC in the head and neck region occur only very rarely. The extremely variable symp tomatology depends on the location of the metastasis and the aff ected structures. This might be a pitfall for dia gnostics, especially in cases of an unidentifi ed primary breast tumor, which may result in a delay of correct dia gnosis. In addition, the correlation between histopathological and clinical fi ndings might be of great relevance in these cases.

Název v anglickém jazyce

Metastases of a Breast Cancer to Skull Base

Popis výsledku anglicky

Background: Breast cancer (BC) is a frequent malignant disease which tends to develop distant metastases, but only very rarely in the head and neck region. Case report: We present two case reports of patients with metastases of invasive BC in this area. They are of different clinical manifestation with different time relation to the primary tumor and different symptomatology. In the case of the first patient, a few years without evidence of malignant disease after treatment of primary tumor in complete remission. In the case of the second patient, as the first symptom of undiagnosed disease. Metastases were clinically observed in the skull base and maxillarysinus, manifest ing neurologically with foramen jugulare syndrome and orbital symptoms, resp. In both cases, correlations between histological and clinical fi ndings were essential for dia gnosis. Palliative multimodal treatment was then employed. Conclusion: Metastases of BC in the head and neck region occur only very rarely. The extremely variable symp tomatology depends on the location of the metastasis and the aff ected structures. This might be a pitfall for dia gnostics, especially in cases of an unidentifi ed primary breast tumor, which may result in a delay of correct dia gnosis. In addition, the correlation between histopathological and clinical fi ndings might be of great relevance in these cases.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30204 - Oncology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Klinická onkologie

ISSN

0862-495X

e-ISSN

—

Svazek periodika

31

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

3

Strana od-do

293-295

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85054636280