Controversies in neuro-oncology: Focal proton versus photon radiation therapy for adult brain tumors

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00209805%3A_____%2F24%3A00079825" target="_blank" >RIV/00209805:_____/24:00079825 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/24:00136201

Výsledek na webu

<a href="https://academic.oup.com/nop/article/11/4/369/7659617?login=true" target="_blank" >https://academic.oup.com/nop/article/11/4/369/7659617?login=true</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/nop/npae040" target="_blank" >10.1093/nop/npae040</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Controversies in neuro-oncology: Focal proton versus photon radiation therapy for adult brain tumors

Popis výsledku v původním jazyce

Radiation therapy (RT) plays a fundamental role in the treatment of malignant and benign brain tumors. Current state-of-the-art photon- and proton-based RT combines more conformal dose distribution of target volumes and accurate dose delivery while limiting the adverse radiation effects. PubMed was systematically searched from from 2000 to October 2023 to identify studies reporting outcomes related to treatment of central nervous system (CNS)/skull base tumors with PT in adults. Several studies have demonstrated that proton therapy (PT) provides a reduced dose to healthy brain parenchyma compared with photon-based (xRT) radiation techniques. However, whether dosimetric advantages translate into superior clinical outcomes for different adult brain tumors remains an open question. This review aims at critically reviewing the recent studies on PT in adult patients with brain tumors, including glioma, meningiomas, and chordomas, to explore its potential benefits compared with xRT.

Název v anglickém jazyce

Controversies in neuro-oncology: Focal proton versus photon radiation therapy for adult brain tumors

Popis výsledku anglicky

Radiation therapy (RT) plays a fundamental role in the treatment of malignant and benign brain tumors. Current state-of-the-art photon- and proton-based RT combines more conformal dose distribution of target volumes and accurate dose delivery while limiting the adverse radiation effects. PubMed was systematically searched from from 2000 to October 2023 to identify studies reporting outcomes related to treatment of central nervous system (CNS)/skull base tumors with PT in adults. Several studies have demonstrated that proton therapy (PT) provides a reduced dose to healthy brain parenchyma compared with photon-based (xRT) radiation techniques. However, whether dosimetric advantages translate into superior clinical outcomes for different adult brain tumors remains an open question. This review aims at critically reviewing the recent studies on PT in adult patients with brain tumors, including glioma, meningiomas, and chordomas, to explore its potential benefits compared with xRT.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30204 - Oncology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neuro-Oncology Practice

ISSN

2054-2577

e-ISSN

2054-2585

Svazek periodika

11

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

14

Strana od-do

369-382

Kód UT WoS článku

001234931700001

EID výsledku v databázi Scopus

2-s2.0-85198967077