Acipimox Exerts a Feedback of GH on Ghrelin in Bulimia Nervosa: Increased Response of Growth Hormone and Ghrelin to Exercise and Anti-Lipolytic Drug in Patients With Bulimia Nervosa

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F13%3A10189983" target="_blank" >RIV/00216208:11110/13:10189983 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023761:_____/13:#0000426

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Acipimox Exerts a Feedback of GH on Ghrelin in Bulimia Nervosa: Increased Response of Growth Hormone and Ghrelin to Exercise and Anti-Lipolytic Drug in Patients With Bulimia Nervosa

Popis výsledku v původním jazyce

The balance and interaction between anorexigenic and orexigenic factors originating from gastrointestinal tract, central nervous system and adipose tissue appear to play an important role in short-term regulation of food intake, energy homeostasis and growth hormone release. An impairment of this balance may result in eating disorders, such as anorexia nervosa and bulimia nervosa (BN). Hence, we will study the effect of exercise alone or together with anti-lipolytic drug Acipimox on the gut-brain-adipose tissue hormone secretion in patients with BN. We will determine relationship between plasma ghrelin, growth hormone, neuropeptide Y and leptin secretion under basal conditions and after physical exercise alone or together with Acipimox administration in patients with BN and healthy women. In vivo microdialysis technique we will use to determine the effect of exercise alone or together with Acipimox administration on local glycerol concentrations in subcutaneous abdominal adipose tissue

Název v anglickém jazyce

Acipimox Exerts a Feedback of GH on Ghrelin in Bulimia Nervosa: Increased Response of Growth Hormone and Ghrelin to Exercise and Anti-Lipolytic Drug in Patients With Bulimia Nervosa

Popis výsledku anglicky

The balance and interaction between anorexigenic and orexigenic factors originating from gastrointestinal tract, central nervous system and adipose tissue appear to play an important role in short-term regulation of food intake, energy homeostasis and growth hormone release. An impairment of this balance may result in eating disorders, such as anorexia nervosa and bulimia nervosa (BN). Hence, we will study the effect of exercise alone or together with anti-lipolytic drug Acipimox on the gut-brain-adipose tissue hormone secretion in patients with BN. We will determine relationship between plasma ghrelin, growth hormone, neuropeptide Y and leptin secretion under basal conditions and after physical exercise alone or together with Acipimox administration in patients with BN and healthy women. In vivo microdialysis technique we will use to determine the effect of exercise alone or together with Acipimox administration on local glycerol concentrations in subcutaneous abdominal adipose tissue

Druh

B - Odborná kniha

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

ISBN

978-3-659-23136-0

Počet stran knihy

172

Název nakladatele

LAP Lambert Academic Publishing

Místo vydání

Saarbrucken

Kód UT WoS knihy

—