Differential Acute Postprandial Effects of Processed Meat and Isocaloric Vegan Meals on the Gastrointestinal Hormone Response in Subjects Suffering from Type 2 Diabetes and Healthy Controls: A Randomized Crossover Study
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10272520" target="_blank" >RIV/00216208:11110/14:10272520 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11140/14:10272520 RIV/00023761:_____/14:#0000445 RIV/00669806:_____/14:10272520 RIV/00023001:_____/14:00059028
Výsledek na webu
<a href="http://dx.doi.org/10.1371/journal.pone.0107561" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0107561</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0107561" target="_blank" >10.1371/journal.pone.0107561</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Differential Acute Postprandial Effects of Processed Meat and Isocaloric Vegan Meals on the Gastrointestinal Hormone Response in Subjects Suffering from Type 2 Diabetes and Healthy Controls: A Randomized Crossover Study
Popis výsledku v původním jazyce
Background: The intake of meat, particularly processed meat, is a dietary risk factor for diabetes. Meat intake impairs insulin sensitivity and leads to increased oxidative stress. However, its effect on postprandial gastrointestinal hormone (GIH) secretion is unclear. We aimed to investigate the acute effects of two standardized isocaloric meals: a processed hamburger meat meal rich in protein and saturated fat (M-meal) and a vegan meal rich in carbohydrates (V-meal). We hypothesized that the meat mealwould lead to abnormal postprandial increases in plasma lipids and oxidative stress markers and impaired GIH responses. Methods: In a randomized crossover study, 50 patients suffering from type 2 diabetes (T2D) and 50 healthy subjects underwent two 3-hmeal tolerance tests. For statistical analyses, repeated-measures ANOVA was performed. Results: The M-meal resulted in a higher postprandial increase in lipids in both groups (p<0.001) and persistent postprandial hyperinsulinemia in patie
Název v anglickém jazyce
Differential Acute Postprandial Effects of Processed Meat and Isocaloric Vegan Meals on the Gastrointestinal Hormone Response in Subjects Suffering from Type 2 Diabetes and Healthy Controls: A Randomized Crossover Study
Popis výsledku anglicky
Background: The intake of meat, particularly processed meat, is a dietary risk factor for diabetes. Meat intake impairs insulin sensitivity and leads to increased oxidative stress. However, its effect on postprandial gastrointestinal hormone (GIH) secretion is unclear. We aimed to investigate the acute effects of two standardized isocaloric meals: a processed hamburger meat meal rich in protein and saturated fat (M-meal) and a vegan meal rich in carbohydrates (V-meal). We hypothesized that the meat mealwould lead to abnormal postprandial increases in plasma lipids and oxidative stress markers and impaired GIH responses. Methods: In a randomized crossover study, 50 patients suffering from type 2 diabetes (T2D) and 50 healthy subjects underwent two 3-hmeal tolerance tests. For statistical analyses, repeated-measures ANOVA was performed. Results: The M-meal resulted in a higher postprandial increase in lipids in both groups (p<0.001) and persistent postprandial hyperinsulinemia in patie
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FB - Endokrinologie, diabetologie, metabolismus, výživa
OECD FORD obor
—
Návaznosti výsledku
Projekt
<a href="/cs/project/NT11238" target="_blank" >NT11238: Dietní intervence u nemocných s diabetem 2. Typu - vliv frekvence a složení jídel na metabolismus glukózy a další projevy metabolického syndromu</a><br>
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
PLoS ONE
ISSN
1932-6203
e-ISSN
—
Svazek periodika
9
Číslo periodika v rámci svazku
9
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
10
Strana od-do
—
Kód UT WoS článku
000341774800083
EID výsledku v databázi Scopus
—