The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10284342" target="_blank" >RIV/00216208:11110/14:10284342 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61383082:_____/14:#0000272 RIV/00216224:14110/14:00075468 RIV/65269705:_____/14:00062681 RIV/00023001:_____/14:00059022 RIV/75010330:_____/14:00010739
Výsledek na webu
<a href="http://dx.doi.org/10.1111/jvh.12248" target="_blank" >http://dx.doi.org/10.1111/jvh.12248</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/jvh.12248" target="_blank" >10.1111/jvh.12248</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm
Popis výsledku v původním jazyce
The disease burden of hepatitis C virus (HCV) is expected to increase as the infected population ages. A modelling approach was used to estimate the total number of viremic infections, diagnosed, treated and new infections in 2013. In addition, the modelwas used to estimate the change in the total number of HCV infections, the disease progression and mortality in 2013-2030. Finally, expert panel consensus was used to capture current treatment practices in each country. Using today's treatment paradigm,the total number of HCV infections is projected to decline or remain flat in all countries studied. However, in the same time period, the number of individuals with late-stage liver disease is projected to increase. This study concluded that the currenttreatment rate and efficacy are not sufficient to manage the disease burden of HCV. Thus, alternative strategies are required to keep the number of HCV individuals with advanced liver disease and liver-related deaths from increasing.
Název v anglickém jazyce
The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm
Popis výsledku anglicky
The disease burden of hepatitis C virus (HCV) is expected to increase as the infected population ages. A modelling approach was used to estimate the total number of viremic infections, diagnosed, treated and new infections in 2013. In addition, the modelwas used to estimate the change in the total number of HCV infections, the disease progression and mortality in 2013-2030. Finally, expert panel consensus was used to capture current treatment practices in each country. Using today's treatment paradigm,the total number of HCV infections is projected to decline or remain flat in all countries studied. However, in the same time period, the number of individuals with late-stage liver disease is projected to increase. This study concluded that the currenttreatment rate and efficacy are not sufficient to manage the disease burden of HCV. Thus, alternative strategies are required to keep the number of HCV individuals with advanced liver disease and liver-related deaths from increasing.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FE - Ostatní obory vnitřního lékařství
OECD FORD obor
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Návaznosti výsledku
Projekt
—
Návaznosti
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of Viral Hepatitis
ISSN
1352-0504
e-ISSN
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Svazek periodika
21
Číslo periodika v rámci svazku
Supp. 1
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
26
Strana od-do
34-59
Kód UT WoS článku
000333893200003
EID výsledku v databázi Scopus
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