Circulating endometrial cells in peripheral blood

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10293102" target="_blank" >RIV/00216208:11110/14:10293102 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/14:43908879 RIV/00064173:_____/14:#0000402 RIV/00064203:_____/14:10293102

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ejogrb.2014.07.037" target="_blank" >http://dx.doi.org/10.1016/j.ejogrb.2014.07.037</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ejogrb.2014.07.037" target="_blank" >10.1016/j.ejogrb.2014.07.037</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Circulating endometrial cells in peripheral blood

Popis výsledku v původním jazyce

Objectives: Endometriosis is a common disorder amongst women of reproductive age. Despite extensive research, no reliable blood tests currently exist for the diagnosis of endometriosis Study design: We report several new approaches enabling study of cellspecific characteristic of endometrial cells, introducing enrichment and culturing of viable circulating endometrial cells (CECs) isolated from peripheral blood (PB) and peritoneal endometrial cells (PECs) from peritoneal washing (PW). Size-based enrichment method (MetaCell (R), Czech Republic) has been used for the filtration of PB and PW in patients with diagnosed endometriosis. Results: The PECs were found in the PW in all of the tested patients (n = 17), but CECs) only in 23.5% (4/17) cases. Theirendometrial origin has been proved by immunohistochemistry. PECs were successfully cultured in vitro directly on the separating membrane (9/17) exhibiting both endometrial cell phenotypes: stromal and glandular within the culture. CECs we

Název v anglickém jazyce

Circulating endometrial cells in peripheral blood

Popis výsledku anglicky

Objectives: Endometriosis is a common disorder amongst women of reproductive age. Despite extensive research, no reliable blood tests currently exist for the diagnosis of endometriosis Study design: We report several new approaches enabling study of cellspecific characteristic of endometrial cells, introducing enrichment and culturing of viable circulating endometrial cells (CECs) isolated from peripheral blood (PB) and peritoneal endometrial cells (PECs) from peritoneal washing (PW). Size-based enrichment method (MetaCell (R), Czech Republic) has been used for the filtration of PB and PW in patients with diagnosed endometriosis. Results: The PECs were found in the PW in all of the tested patients (n = 17), but CECs) only in 23.5% (4/17) cases. Theirendometrial origin has been proved by immunohistochemistry. PECs were successfully cultured in vitro directly on the separating membrane (9/17) exhibiting both endometrial cell phenotypes: stromal and glandular within the culture. CECs we

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

—

Projekt

<a href="/cs/project/NT14441" target="_blank" >NT14441: Cirkulující a diseminované nádorové buňky v diagnostice a léčbě pokročilých stadií karcinomu ovaria</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Obstetrics, Gynecology and Reproductive Biology

ISSN

0301-2115

e-ISSN

—

Svazek periodika

181

Číslo periodika v rámci svazku

neuveden

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

267-274

Kód UT WoS článku

000343952000048

EID výsledku v databázi Scopus

—