Sharp-wave EEG abnormalities and neural complexity in depressive patients: preliminary report

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F15%3A10321379" target="_blank" >RIV/00216208:11110/15:10321379 - isvavai.cz</a>

Výsledek na webu

<a href="http://link.springer.com/content/pdf/10.1186%2Fs40810-015-0011-y.pdf" target="_blank" >http://link.springer.com/content/pdf/10.1186%2Fs40810-015-0011-y.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s40810-015-0011-y" target="_blank" >10.1186/s40810-015-0011-y</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Sharp-wave EEG abnormalities and neural complexity in depressive patients: preliminary report

Popis výsledku v původním jazyce

Background: According to recent findings cognitive and emotional dysregulation in depression and psychiatric disorders may be related to deficits in inhibitory functions and temporo-limbic seizure-like activity due to specific changes in neural dynamicsand complexity of neural networks. Methods: In order to evaluate the clinical utility of nonlinear analysis of EEG complexity (measured by Lyapunov exponents) and to assess underlying epileptiform changes, we studied a sample of 19 depressive patients including nine depressive patients with episodic sharp-wave EEG abnormalities and ten depressive patients without any abnormalities, and compared also subgroups of these patients who used benzodiazepine medication to assess its influence on EEG complexity.Results and findings: The results show that the depressive patients with episodic sharp-wave EEG abnormalities had significantly lower EEG complexity than the control groups of patients. The data also indicate that benzodiazepines signif

Název v anglickém jazyce

Sharp-wave EEG abnormalities and neural complexity in depressive patients: preliminary report

Popis výsledku anglicky

Background: According to recent findings cognitive and emotional dysregulation in depression and psychiatric disorders may be related to deficits in inhibitory functions and temporo-limbic seizure-like activity due to specific changes in neural dynamicsand complexity of neural networks. Methods: In order to evaluate the clinical utility of nonlinear analysis of EEG complexity (measured by Lyapunov exponents) and to assess underlying epileptiform changes, we studied a sample of 19 depressive patients including nine depressive patients with episodic sharp-wave EEG abnormalities and ten depressive patients without any abnormalities, and compared also subgroups of these patients who used benzodiazepine medication to assess its influence on EEG complexity.Results and findings: The results show that the depressive patients with episodic sharp-wave EEG abnormalities had significantly lower EEG complexity than the control groups of patients. The data also indicate that benzodiazepines signif

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FL - Psychiatrie, sexuologie

OECD FORD obor

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Projekt

<a href="/cs/project/GAP407%2F12%2F1957" target="_blank" >GAP407/12/1957: Autonomní indikátory predikce stresové odpovědi</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neuropsychiatric Electrophysiology

ISSN

2055-4788

e-ISSN

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Svazek periodika

1

Číslo periodika v rámci svazku

December

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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