Safety and efficacy of endovascular treatment for intracranial infectious aneurysms: A systematic review and meta-analysis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F16%3A10328390" target="_blank" >RIV/00216208:11110/16:10328390 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.neurad.2016.03.008" target="_blank" >http://dx.doi.org/10.1016/j.neurad.2016.03.008</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.neurad.2016.03.008" target="_blank" >10.1016/j.neurad.2016.03.008</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Safety and efficacy of endovascular treatment for intracranial infectious aneurysms: A systematic review and meta-analysis

Popis výsledku v původním jazyce

Introduction: Intracranial infectious aneurysms (IIAs), or mycotic aneurysms are rare, representing between 0.7% and 5.4% of all intracranial aneurysms. To clarify the safety and efficacy of endovascular treatment of IIAs, we conducted a systematic review of the literature analyzing periprocedural and long-term clinical and angiographic outcomes. Methods: A comprehensive review of the literature for studies with >= 3 patients related to endovascular treatment of IIAs published through September 2015 was performed. Random effects meta-analysis was used to pool the following outcomes: complete occlusion, technical success, aneurysm recurrence, rebleeding, perioperative mortality, iatrogenic rupture, perioperative stroke, procedure-related morbidity and mortality, long-term neurological morbidity and mortality, and overall good neurological outcome. Results: We included 11 non-comparative studies with 86 target IIAs. Complete occlusion rates were 95.3% (95% CI = 91.2-99.4%). Recurrence occurred in 7.9% (95% CI = 2.7-13.0%). Rebleeding occurred in 5.8% (95% CI = 1.4-10.3%) of patients. Procedure-related morbidity was 12.6% (95% CI = 6.1-19.2%) and procedure-related mortality was 6.1% (95% CI = 1.5-10.8%). Long-term good neurological outcome was 68.0% (95% CI = 55.1-80.9%). Conclusion: Our meta-analysis demonstrated that endovascular treatment is technically feasible and effective with high rates of IIA occlusion. Despite the comorbidities of patients, endovascular approach was associated with acceptable rates of procedure-related morbidity and satisfactory rates of overall good neurological outcome.

Název v anglickém jazyce

Safety and efficacy of endovascular treatment for intracranial infectious aneurysms: A systematic review and meta-analysis

Popis výsledku anglicky

Introduction: Intracranial infectious aneurysms (IIAs), or mycotic aneurysms are rare, representing between 0.7% and 5.4% of all intracranial aneurysms. To clarify the safety and efficacy of endovascular treatment of IIAs, we conducted a systematic review of the literature analyzing periprocedural and long-term clinical and angiographic outcomes. Methods: A comprehensive review of the literature for studies with >= 3 patients related to endovascular treatment of IIAs published through September 2015 was performed. Random effects meta-analysis was used to pool the following outcomes: complete occlusion, technical success, aneurysm recurrence, rebleeding, perioperative mortality, iatrogenic rupture, perioperative stroke, procedure-related morbidity and mortality, long-term neurological morbidity and mortality, and overall good neurological outcome. Results: We included 11 non-comparative studies with 86 target IIAs. Complete occlusion rates were 95.3% (95% CI = 91.2-99.4%). Recurrence occurred in 7.9% (95% CI = 2.7-13.0%). Rebleeding occurred in 5.8% (95% CI = 1.4-10.3%) of patients. Procedure-related morbidity was 12.6% (95% CI = 6.1-19.2%) and procedure-related mortality was 6.1% (95% CI = 1.5-10.8%). Long-term good neurological outcome was 68.0% (95% CI = 55.1-80.9%). Conclusion: Our meta-analysis demonstrated that endovascular treatment is technically feasible and effective with high rates of IIA occlusion. Despite the comorbidities of patients, endovascular approach was associated with acceptable rates of procedure-related morbidity and satisfactory rates of overall good neurological outcome.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

—

Projekt

—

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Neuroradiology

ISSN

0150-9861

e-ISSN

—

Svazek periodika

43

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

FR - Francouzská republika

Počet stran výsledku

8

Strana od-do

309-316

Kód UT WoS článku

000385471700002

EID výsledku v databázi Scopus

2-s2.0-84964644474