Relapse in schizophrenia: Definitively not a bolt from the blue

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F18%3A10375611" target="_blank" >RIV/00216208:11110/18:10375611 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/67985807:_____/18:00473672 RIV/00216208:11120/18:43912823 RIV/68407700:21230/18:00300838 RIV/00023752:_____/18:43914999 RIV/00064165:_____/18:10375611

Výsledek na webu

<a href="https://doi.org/10.1016/j.neulet.2016.04.044" target="_blank" >https://doi.org/10.1016/j.neulet.2016.04.044</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.neulet.2016.04.044" target="_blank" >10.1016/j.neulet.2016.04.044</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Relapse in schizophrenia: Definitively not a bolt from the blue

Popis výsledku v původním jazyce

Detailed study of the period before schizophrenic relapse when early warning signs (EWS) are present is crucial to effective pre-emptive strategies. To investigate the temporal properties of EWS self-reported weekly via a telemedicine system. EWS history was obtained for 61 relapses resulting in hospitalization involving 51 patients with schizophrenia. Up to 20 weeks of EWS history per case were evaluated using a non-parametric bootstrap test and generalized mixed-effects model to test the significance and homogeneity of the findings. A statistically significant increase in EWS sum score was detectable 5 weeks before hospitalization. However, analysis of EWS dynamics revealed a gradual, monotonic increase in EWS score across during the 8 weeks before a relapse. The findings in contrast to earlier studies suggest that relapse is preceded by a lengthy period during which pathophysiological processes unfold; these changes are reflected in subjective EWS.

Název v anglickém jazyce

Relapse in schizophrenia: Definitively not a bolt from the blue

Popis výsledku anglicky

Detailed study of the period before schizophrenic relapse when early warning signs (EWS) are present is crucial to effective pre-emptive strategies. To investigate the temporal properties of EWS self-reported weekly via a telemedicine system. EWS history was obtained for 61 relapses resulting in hospitalization involving 51 patients with schizophrenia. Up to 20 weeks of EWS history per case were evaluated using a non-parametric bootstrap test and generalized mixed-effects model to test the significance and homogeneity of the findings. A statistically significant increase in EWS sum score was detectable 5 weeks before hospitalization. However, analysis of EWS dynamics revealed a gradual, monotonic increase in EWS score across during the 8 weeks before a relapse. The findings in contrast to earlier studies suggest that relapse is preceded by a lengthy period during which pathophysiological processes unfold; these changes are reflected in subjective EWS.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30215 - Psychiatry

Projekt

<a href="/cs/project/NT14387" target="_blank" >NT14387: Predikce relapsu bipolární afektivní poruchy pomocí telemetrického sledování změn sociální rytmicity.</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neuroscience Letters

ISSN

0304-3940

e-ISSN

—

Svazek periodika

669

Číslo periodika v rámci svazku

March

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

7

Strana od-do

68-74

Kód UT WoS článku

000430774400010

EID výsledku v databázi Scopus

2-s2.0-84964864133