Test the Best: Classification Accuracies of Four Cognitive Rating Scales for Parkinson's Disease Mild Cognitive Impairment

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F20%3A10412704" target="_blank" >RIV/00216208:11110/20:10412704 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/20:10412704 RIV/00064165:_____/20:10412704

Výsledek na webu

<a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=17jZybvK8x" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=17jZybvK8x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/arclin/acaa039" target="_blank" >10.1093/arclin/acaa039</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Test the Best: Classification Accuracies of Four Cognitive Rating Scales for Parkinson's Disease Mild Cognitive Impairment

Popis výsledku v původním jazyce

OBJECTIVE: A progressive cognitive impairment is one of the frequent non-motor symptoms during Parkinson&apos;s disease (PD) course. A short and valid screening tool is needed to detect an incipient cognitive deficit at the mild cognitive impairment stage in Parkinson&apos;s disease (PD-MCI). METHOD: The present study aims to evaluate the classification accuracies of four cognitive screenings: Montreal Cognitive Assessment (MoCA), Mattis Dementia Rating Scale second edition (DRS-2), Mini-Mental State Examination (MMSE) and Frontal Assessment Battery (FAB) in a cohort of PD patients (PD-MCI, n = 46; and Parkinson&apos;s disease with normal cognition, PD-NC, n = 95) and Controls (n = 66). All subjects underwent a standard neuropsychological battery as recommended by the International Parkinson and Movement Disorder Society and underwent all four screening tools. RESULTS: In the detection of PD-MCI versus PD-NC, the MoCA showed a sensitivity of 84% and a specificity of 66% with a screening cutoff score at &lt;=25 points. The MoCA&apos;s AUC was 86% (95% CI 78.7-93.1). In the detection of PD-MCI versus Controls, the FAB displayed 84% sensitivity and 79% specificity with a cutoff &lt;=16 points, to screen. The FAB&apos;s AUC was 87% (79.0-95.0). CONCLUSIONS: Our results show that the MoCA is the most discriminative tool for screening MCI in the PD population.

Název v anglickém jazyce

Test the Best: Classification Accuracies of Four Cognitive Rating Scales for Parkinson's Disease Mild Cognitive Impairment

Popis výsledku anglicky

OBJECTIVE: A progressive cognitive impairment is one of the frequent non-motor symptoms during Parkinson&apos;s disease (PD) course. A short and valid screening tool is needed to detect an incipient cognitive deficit at the mild cognitive impairment stage in Parkinson&apos;s disease (PD-MCI). METHOD: The present study aims to evaluate the classification accuracies of four cognitive screenings: Montreal Cognitive Assessment (MoCA), Mattis Dementia Rating Scale second edition (DRS-2), Mini-Mental State Examination (MMSE) and Frontal Assessment Battery (FAB) in a cohort of PD patients (PD-MCI, n = 46; and Parkinson&apos;s disease with normal cognition, PD-NC, n = 95) and Controls (n = 66). All subjects underwent a standard neuropsychological battery as recommended by the International Parkinson and Movement Disorder Society and underwent all four screening tools. RESULTS: In the detection of PD-MCI versus PD-NC, the MoCA showed a sensitivity of 84% and a specificity of 66% with a screening cutoff score at &lt;=25 points. The MoCA&apos;s AUC was 86% (95% CI 78.7-93.1). In the detection of PD-MCI versus Controls, the FAB displayed 84% sensitivity and 79% specificity with a cutoff &lt;=16 points, to screen. The FAB&apos;s AUC was 87% (79.0-95.0). CONCLUSIONS: Our results show that the MoCA is the most discriminative tool for screening MCI in the PD population.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

<a href="/cs/project/NV19-04-00233" target="_blank" >NV19-04-00233: Klinické, zobrazovací a biologické prediktory účinků hluboké mozkové stimulace u Parkinsonovy nemoci</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Archives of Clinical Neuropsychology

ISSN

0887-6177

e-ISSN

—

Svazek periodika

35

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

1069-1077

Kód UT WoS článku

000595486600002

EID výsledku v databázi Scopus

2-s2.0-85096106408