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COVID-19 symptom duration predicts immunoglobulin G seropositivity

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F21%3A10435514" target="_blank" >RIV/00216208:11110/21:10435514 - isvavai.cz</a>

  • Nalezeny alternativní kódy

    RIV/00098892:_____/21:N0000249 RIV/61989592:15110/21:73608302

  • Výsledek na webu

    <a href="https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=7EGVxC85fF" target="_blank" >https://verso.is.cuni.cz/pub/verso.fpl?fname=obd_publikace_handle&handle=7EGVxC85fF</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.4149/BLL_2021_139" target="_blank" >10.4149/BLL_2021_139</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    COVID-19 symptom duration predicts immunoglobulin G seropositivity

  • Popis výsledku v původním jazyce

    OBJECTIVES: The study focused on the relationship between routine clinical characteristics and anti-SARSCoV-2 specifi c antibodies in a pilot sample of healthcare workers (HCWs) having suffered COVID-19. The aim was to investigate the existence of readily available predictors of antibodies against COVID-19. METHODS: As part of the recognition of COVID-19 as an occupational disease in 152 HCWs with the mean age of 43.2 years, personal, anthropometric and anamnestic data related to the disease as well as anti-spike immunoglobulin (Ig) levels were obtained. Through descriptive statistics, correlation and regression analyses, relationships of all variables and Ig levels, especially seropositivity of IgG, were investigated. RESULTS: The mean interval between the symptom onset and the determination of antibodies was 58 days. IgG seropositivity and IgM seropositivity were noted in 82 % and 49 % of HCWs, respectively. Symptom duration was the only statistically signifi cant predictor of IgG seropositivity. With each day of symptom duration, the probability of IgG seropositivity increased from 1.078 to 1.092 times (p &lt; 0.05). If symptoms lasted longer than 17 days, a majority (almost 80 %) of the subjects demonstrated seropositivity in the following months. CONCLUSION: The presence of IgG immunity may be assumed from symptom duration. Such easy recognizing of seropositive patients may be a useful tool, e.g. in vaccination strategies (Tab. 3, Fig. 1, Ref. 28). Text in PDF www.elis.sk

  • Název v anglickém jazyce

    COVID-19 symptom duration predicts immunoglobulin G seropositivity

  • Popis výsledku anglicky

    OBJECTIVES: The study focused on the relationship between routine clinical characteristics and anti-SARSCoV-2 specifi c antibodies in a pilot sample of healthcare workers (HCWs) having suffered COVID-19. The aim was to investigate the existence of readily available predictors of antibodies against COVID-19. METHODS: As part of the recognition of COVID-19 as an occupational disease in 152 HCWs with the mean age of 43.2 years, personal, anthropometric and anamnestic data related to the disease as well as anti-spike immunoglobulin (Ig) levels were obtained. Through descriptive statistics, correlation and regression analyses, relationships of all variables and Ig levels, especially seropositivity of IgG, were investigated. RESULTS: The mean interval between the symptom onset and the determination of antibodies was 58 days. IgG seropositivity and IgM seropositivity were noted in 82 % and 49 % of HCWs, respectively. Symptom duration was the only statistically signifi cant predictor of IgG seropositivity. With each day of symptom duration, the probability of IgG seropositivity increased from 1.078 to 1.092 times (p &lt; 0.05). If symptoms lasted longer than 17 days, a majority (almost 80 %) of the subjects demonstrated seropositivity in the following months. CONCLUSION: The presence of IgG immunity may be assumed from symptom duration. Such easy recognizing of seropositive patients may be a useful tool, e.g. in vaccination strategies (Tab. 3, Fig. 1, Ref. 28). Text in PDF www.elis.sk

Klasifikace

  • Druh

    J<sub>imp</sub> - Článek v periodiku v databázi Web of Science

  • CEP obor

  • OECD FORD obor

    10610 - Biophysics

Návaznosti výsledku

  • Projekt

  • Návaznosti

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Ostatní

  • Rok uplatnění

    2021

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název periodika

    Bratislavské lekárske listy / Bratislava Medical Journal

  • ISSN

    0006-9248

  • e-ISSN

  • Svazek periodika

    122

  • Číslo periodika v rámci svazku

    12

  • Stát vydavatele periodika

    SK - Slovenská republika

  • Počet stran výsledku

    5

  • Strana od-do

    861-865

  • Kód UT WoS článku

    000731753700004

  • EID výsledku v databázi Scopus

    2-s2.0-85122558074