Role of the PPAR alpha Leu162Val and PPAR gamma 2 Pro12Ala Gene Polymorphisms in Weight Change after 2.5-Year Follow-up in Czech Obese Women

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F10%3A00002494" target="_blank" >RIV/00216208:11120/10:00002494 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Role of the PPAR alpha Leu162Val and PPAR gamma 2 Pro12Ala Gene Polymorphisms in Weight Change after 2.5-Year Follow-up in Czech Obese Women

Popis výsledku v původním jazyce

The aim of this study was to investigate the possible effect of PPAR alpha and PPAR gamma 2 variants on weight and eating attitudes as well as on their changes after 2.5-year follow-up. The study was carried out in 246 Czech non-diabetic obese women (age49.0 +/- 11.9 years; BMI 38.1 +/- 7.0 kg/m(2)). The comprehensive weight management programme included low-energy diet, increased physical activity and lifestyle modification. Anthropometric parameters (body weight and height, waist and hip circumferences) and body composition were measured. The Three-Factor Eating Questionnaire and Beck Depression Inventory were evaluated. At baseline and after the follow-up period, fasting levels of serum glucose, plasma adiponectin, ghrelin, leptin, and lipid profile were determined. The dependence of monitored parameters on the Pro12Ala in PPAR gamma 2 and Leu162Val in PPARa and stage of the treatment (baseline; 2.5-year follow-up) was evaluated using the repeated measures ANOVA model. The cohort w

Název v anglickém jazyce

Role of the PPAR alpha Leu162Val and PPAR gamma 2 Pro12Ala Gene Polymorphisms in Weight Change after 2.5-Year Follow-up in Czech Obese Women

Popis výsledku anglicky

The aim of this study was to investigate the possible effect of PPAR alpha and PPAR gamma 2 variants on weight and eating attitudes as well as on their changes after 2.5-year follow-up. The study was carried out in 246 Czech non-diabetic obese women (age49.0 +/- 11.9 years; BMI 38.1 +/- 7.0 kg/m(2)). The comprehensive weight management programme included low-energy diet, increased physical activity and lifestyle modification. Anthropometric parameters (body weight and height, waist and hip circumferences) and body composition were measured. The Three-Factor Eating Questionnaire and Beck Depression Inventory were evaluated. At baseline and after the follow-up period, fasting levels of serum glucose, plasma adiponectin, ghrelin, leptin, and lipid profile were determined. The dependence of monitored parameters on the Pro12Ala in PPAR gamma 2 and Leu162Val in PPARa and stage of the treatment (baseline; 2.5-year follow-up) was evaluated using the repeated measures ANOVA model. The cohort w

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Folia Biologica

ISSN

0015-5500

e-ISSN

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Svazek periodika

56

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

8

Strana od-do

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Kód UT WoS článku

000279493800004

EID výsledku v databázi Scopus

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