Virological and autopsy findings in suspected and confirmed fatal cases of 2009 H1N1 pandemic influenza in the Czech Republic - preliminary results

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F11%3A00003277" target="_blank" >RIV/00216208:11120/11:00003277 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/75010330:_____/11:00009329

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Virological and autopsy findings in suspected and confirmed fatal cases of 2009 H1N1 pandemic influenza in the Czech Republic - preliminary results

Popis výsledku v původním jazyce

Influenza viruses cause substantial morbidity and mortality. Pandemic influenza may have a serious impact on certain (mainly younger) age groups in comparison with seasonal flu. The aim of this study was to analyze and compare virological and autopsy findings in patients who died with suspected or confirmed 2009 H1N1 pandemic influenza virus infection. Postmortem biological samples were collected from any patient who had died with suspected influenza infection to be tested for respiratory viruses. The samples were screened for 2009 H1N1 pandemic influenza virus by real-time PCR (RT PCR) and when RT PCR positive, by virus isolation assay. Other important respiratory viruses such as respiratory syncytial virus, parainfluenza viruses and adenoviruses weredetected by virus isolation assay in a suitable cell culture. Epidemiological analysis of postmortem histopathologic findings in the airway tissue was carried out in 57 of 61 fatal cases. Virological findings were subsequently correlated

Název v anglickém jazyce

Virological and autopsy findings in suspected and confirmed fatal cases of 2009 H1N1 pandemic influenza in the Czech Republic - preliminary results

Popis výsledku anglicky

Influenza viruses cause substantial morbidity and mortality. Pandemic influenza may have a serious impact on certain (mainly younger) age groups in comparison with seasonal flu. The aim of this study was to analyze and compare virological and autopsy findings in patients who died with suspected or confirmed 2009 H1N1 pandemic influenza virus infection. Postmortem biological samples were collected from any patient who had died with suspected influenza infection to be tested for respiratory viruses. The samples were screened for 2009 H1N1 pandemic influenza virus by real-time PCR (RT PCR) and when RT PCR positive, by virus isolation assay. Other important respiratory viruses such as respiratory syncytial virus, parainfluenza viruses and adenoviruses weredetected by virus isolation assay in a suitable cell culture. Epidemiological analysis of postmortem histopathologic findings in the airway tissue was carried out in 57 of 61 fatal cases. Virological findings were subsequently correlated

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FN - Epidemiologie, infekční nemoci a klinická imunologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Influenza and Other Respiratory Viruses

ISSN

1750-2640

e-ISSN

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Svazek periodika

5

Číslo periodika v rámci svazku

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Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

2

Strana od-do

130-131

Kód UT WoS článku

000289296200043

EID výsledku v databázi Scopus

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