Long-term combination therapy of ustekinumab and dapsone in a patient with psoriasis and dermatitis herpetiformis Duhring

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43906095" target="_blank" >RIV/00216208:11120/12:43906095 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064173:_____/12:43906095

Výsledek na webu

<a href="http://dx.doi.org/10.1111/j.1346-8138.2012.01630.x" target="_blank" >http://dx.doi.org/10.1111/j.1346-8138.2012.01630.x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1346-8138.2012.01630.x" target="_blank" >10.1111/j.1346-8138.2012.01630.x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Long-term combination therapy of ustekinumab and dapsone in a patient with psoriasis and dermatitis herpetiformis Duhring

Popis výsledku v původním jazyce

Psoriasis vulgaris is recently associated with other comorbidities like metabolic syndrome and cardiovascular disease. Some studies have also shown connection to celiac disease, a multisystemic disorder associated with skin manifestations like dermatitisherpetiformis Duhring as well as the systemic symptoms. Coexistence of psoriasis vulgaris and celiac disease has been supported by strong evidence. Cianci et al. have shown an increased frequency of Ig heavy-chain HS1,2-A enhancer *2 allele in dermatitis herpetiformis, plaque psoriasis and psoriatic arthritis which suggests a related genetic predisposition in the pathogenesis of these diseases. On the other hand, association with dermatitis herpetiformis is very rare with only some anecdotal reports. Most of these patients were treated only by gluten-free diet or in combination with dapsone. To the best of our knowledge, none of these patients had been on a biologic agent and therefore there is no clinical evidence so far on the safety

Název v anglickém jazyce

Long-term combination therapy of ustekinumab and dapsone in a patient with psoriasis and dermatitis herpetiformis Duhring

Popis výsledku anglicky

Psoriasis vulgaris is recently associated with other comorbidities like metabolic syndrome and cardiovascular disease. Some studies have also shown connection to celiac disease, a multisystemic disorder associated with skin manifestations like dermatitisherpetiformis Duhring as well as the systemic symptoms. Coexistence of psoriasis vulgaris and celiac disease has been supported by strong evidence. Cianci et al. have shown an increased frequency of Ig heavy-chain HS1,2-A enhancer *2 allele in dermatitis herpetiformis, plaque psoriasis and psoriatic arthritis which suggests a related genetic predisposition in the pathogenesis of these diseases. On the other hand, association with dermatitis herpetiformis is very rare with only some anecdotal reports. Most of these patients were treated only by gluten-free diet or in combination with dapsone. To the best of our knowledge, none of these patients had been on a biologic agent and therefore there is no clinical evidence so far on the safety

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FO - Dermatovenerologie

OECD FORD obor

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Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Dermatology

ISSN

0385-2407

e-ISSN

—

Svazek periodika

39

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

2

Strana od-do

1074-1075

Kód UT WoS článku

000311615300001

EID výsledku v databázi Scopus

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