Celiac disease markers in patients with liver diseases: A single center large scale screening study
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F12%3A43906838" target="_blank" >RIV/00216208:11120/12:43906838 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/61388971:_____/12:00388690 RIV/00064173:_____/12:43906838 RIV/00023001:_____/12:00056069
Výsledek na webu
<a href="http://dx.doi.org/10.3748/wjg.v18.i43.6255" target="_blank" >http://dx.doi.org/10.3748/wjg.v18.i43.6255</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3748/wjg.v18.i43.6255" target="_blank" >10.3748/wjg.v18.i43.6255</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Celiac disease markers in patients with liver diseases: A single center large scale screening study
Popis výsledku v původním jazyce
To study the coincidence of celiac disease, we tested its serological markers in patients with various liver diseases. METHODS: Large-scale screening of serum antibodies against tissue transglutaminase (tTG), and deamidated gliadin using enzyme-linked immunosorbent assay and serum antibodies against endomysium using immunohistochemistry, in patients with various liver diseases (n = 962) and patients who underwent liver transplantation (OLTx, n = 523) was performed. The expression of tTG in liver tissuesamples of patients simultaneously suffering from celiac disease and from various liver diseases using immunohistochemistry was carried out. The final diagnosis of celiac disease was confirmed by histological analysis of small-intestinal biopsy. RESULTS:We found that 29 of 962 patients (3%) with liver diseases and 5 of 523 patients (0.8%) who underwent OLTx were seropositive for IgA and IgG anti-tTG antibodies. However, celiac disease was biopsy-diagnosed in 16 patients: 4 with autoimmu
Název v anglickém jazyce
Celiac disease markers in patients with liver diseases: A single center large scale screening study
Popis výsledku anglicky
To study the coincidence of celiac disease, we tested its serological markers in patients with various liver diseases. METHODS: Large-scale screening of serum antibodies against tissue transglutaminase (tTG), and deamidated gliadin using enzyme-linked immunosorbent assay and serum antibodies against endomysium using immunohistochemistry, in patients with various liver diseases (n = 962) and patients who underwent liver transplantation (OLTx, n = 523) was performed. The expression of tTG in liver tissuesamples of patients simultaneously suffering from celiac disease and from various liver diseases using immunohistochemistry was carried out. The final diagnosis of celiac disease was confirmed by histological analysis of small-intestinal biopsy. RESULTS:We found that 29 of 962 patients (3%) with liver diseases and 5 of 523 patients (0.8%) who underwent OLTx were seropositive for IgA and IgG anti-tTG antibodies. However, celiac disease was biopsy-diagnosed in 16 patients: 4 with autoimmu
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FE - Ostatní obory vnitřního lékařství
OECD FORD obor
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Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
World Journal of Gastroenterology
ISSN
1007-9327
e-ISSN
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Svazek periodika
18
Číslo periodika v rámci svazku
43
Stát vydavatele periodika
CN - Čínská lidová republika
Počet stran výsledku
8
Strana od-do
6255-6262
Kód UT WoS článku
000311522700011
EID výsledku v databázi Scopus
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