Multiple adenomatous duodenal polyposis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F13%3A43907259" target="_blank" >RIV/00216208:11120/13:43907259 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1155/2013/181704" target="_blank" >http://dx.doi.org/10.1155/2013/181704</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2013/181704" target="_blank" >10.1155/2013/181704</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Multiple adenomatous duodenal polyposis

Popis výsledku v původním jazyce

Multiple duodenal polyps are a relatively rare finding, usually co-occurrent with familial adenomatous polyposis (FAP).We report a patient with multiple duodenal adenomas and a negative examination for FAP: multiple flat polyps were detected endoscopically in a 37-year-old male patient, extending from the apex of the bulb to the end of the descending part of the duodenum. In terms of histology, they were tubular adenomas with moderate dysplasia. Colonoscopy and enteroclysis were normal. Both push and capsule enteroscopy only showed multiple polyps in the area of the descending duodenum. DNA analysis of the APC gene was as follows: DGGE, exon 1?15, deletion at codons 1309 and 1061 by means of PCR for attenuated APC were negative. Afterwards we screenedthe patient for germline MYH mutations using the denaturing high-performance liquid chromatography (DHPLC) in combination with sequencing. No novel pathogenic mutation has been identified. Large polyps were removed by means of endoscopic

Název v anglickém jazyce

Multiple adenomatous duodenal polyposis

Popis výsledku anglicky

Multiple duodenal polyps are a relatively rare finding, usually co-occurrent with familial adenomatous polyposis (FAP).We report a patient with multiple duodenal adenomas and a negative examination for FAP: multiple flat polyps were detected endoscopically in a 37-year-old male patient, extending from the apex of the bulb to the end of the descending part of the duodenum. In terms of histology, they were tubular adenomas with moderate dysplasia. Colonoscopy and enteroclysis were normal. Both push and capsule enteroscopy only showed multiple polyps in the area of the descending duodenum. DNA analysis of the APC gene was as follows: DGGE, exon 1?15, deletion at codons 1309 and 1061 by means of PCR for attenuated APC were negative. Afterwards we screenedthe patient for germline MYH mutations using the denaturing high-performance liquid chromatography (DHPLC) in combination with sequencing. No novel pathogenic mutation has been identified. Large polyps were removed by means of endoscopic

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Case Reports in Gastrointestinal Medicine (On-line)

ISSN

2090-6536

e-ISSN

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Svazek periodika

2013

Číslo periodika v rámci svazku

Art. ID. 181704

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

3

Strana od-do

1-3

Kód UT WoS článku

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EID výsledku v databázi Scopus

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