Blood pressure changes after renal denervation at 10 European expert centers

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F14%3A43908337" target="_blank" >RIV/00216208:11120/14:43908337 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/14:10288560 RIV/00064165:_____/14:10288560

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Blood pressure changes after renal denervation at 10 European expert centers

Popis výsledku v původním jazyce

We did a subject-level meta-analysis of the changes (Delta) in blood pressure (BP) observed 3 and 6 months after renal denervation (RDN) at 10 European centers. Recruited patients (n = 109; 46.8% women; mean age 58.2 years) had essential hypertension confirmed by ambulatory BP. From baseline to 6 months, treatment score declined slightly from 4.7 to 4.4 drugs per day. Systolic/diastolic BP fell by 17.6/7.1 mm Hg for office BP, and by 5.9/3.5, 6.2/3.4, and 4.4/2.5mmHg for 24-h, daytime and nighttime BP (P <= 0.03 for all). In 47 patients with 3-and 6-month ambulatory measurements, systolic BP did not change between these two time points (P <= 0.08). Normalization was a systolic BP of <140mm Hg on office measurement or <130 mm Hg on 24-h monitoring and improvement was a fall of <= 10 mm Hg, irrespective of measurement technique. For office BP, at 6 months, normalization, improvement or no decrease occurred in 22.9, 59.6 and 22.9% of patients, respectively; for 24-h BP, these proportions

Název v anglickém jazyce

Blood pressure changes after renal denervation at 10 European expert centers

Popis výsledku anglicky

We did a subject-level meta-analysis of the changes (Delta) in blood pressure (BP) observed 3 and 6 months after renal denervation (RDN) at 10 European centers. Recruited patients (n = 109; 46.8% women; mean age 58.2 years) had essential hypertension confirmed by ambulatory BP. From baseline to 6 months, treatment score declined slightly from 4.7 to 4.4 drugs per day. Systolic/diastolic BP fell by 17.6/7.1 mm Hg for office BP, and by 5.9/3.5, 6.2/3.4, and 4.4/2.5mmHg for 24-h, daytime and nighttime BP (P <= 0.03 for all). In 47 patients with 3-and 6-month ambulatory measurements, systolic BP did not change between these two time points (P <= 0.08). Normalization was a systolic BP of <140mm Hg on office measurement or <130 mm Hg on 24-h monitoring and improvement was a fall of <= 10 mm Hg, irrespective of measurement technique. For office BP, at 6 months, normalization, improvement or no decrease occurred in 22.9, 59.6 and 22.9% of patients, respectively; for 24-h BP, these proportions

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

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Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Human Hypertension

ISSN

0950-9240

e-ISSN

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Svazek periodika

28

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

150-156

Kód UT WoS článku

000331618200003

EID výsledku v databázi Scopus

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