Insulin resistance and outcome in bipolar disorder
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909413" target="_blank" >RIV/00216208:11120/15:43909413 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1192/bjp.bp.114.152850" target="_blank" >http://dx.doi.org/10.1192/bjp.bp.114.152850</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1192/bjp.bp.114.152850" target="_blank" >10.1192/bjp.bp.114.152850</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Insulin resistance and outcome in bipolar disorder
Popis výsledku v původním jazyce
Background: Little is known about the impact of insulin resistance on bipolar disorder. Aims: To examine the relationships between insulin resistance, type 2 diabetes and clinical course and treatment outcomes in bipolar disorder. Method: We measured fasting glucose and insulin in 121 adults with bipolar disorder. We diagnosed type 2 diabetes and determined insulin resistance. The National Institute of Mental Health Life Chart was used to record the course of bipolar disorder and the Alda scale to establish response to prophylactic lithium treatment. Results: Patients with bipolar disorder and type 2 diabetes or insulin resistance had three times higher odds of a chronic course of bipolar disorder compared with euglycaemic patients (50% and 48.7% respectively v. 27.3%, odds ratio (OR) = 3.07, P = 0.007), three times higher odds of rapid cycling (38.5% and 39.5% respectively v. 18.2%, OR = 3.13, P = 0.012) and were more likely to be refractory to lithium treatment (36.8% and 36.7% respe
Název v anglickém jazyce
Insulin resistance and outcome in bipolar disorder
Popis výsledku anglicky
Background: Little is known about the impact of insulin resistance on bipolar disorder. Aims: To examine the relationships between insulin resistance, type 2 diabetes and clinical course and treatment outcomes in bipolar disorder. Method: We measured fasting glucose and insulin in 121 adults with bipolar disorder. We diagnosed type 2 diabetes and determined insulin resistance. The National Institute of Mental Health Life Chart was used to record the course of bipolar disorder and the Alda scale to establish response to prophylactic lithium treatment. Results: Patients with bipolar disorder and type 2 diabetes or insulin resistance had three times higher odds of a chronic course of bipolar disorder compared with euglycaemic patients (50% and 48.7% respectively v. 27.3%, odds ratio (OR) = 3.07, P = 0.007), three times higher odds of rapid cycling (38.5% and 39.5% respectively v. 18.2%, OR = 3.13, P = 0.012) and were more likely to be refractory to lithium treatment (36.8% and 36.7% respe
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FH - Neurologie, neurochirurgie, neurovědy
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
British Journal of Psychiatry
ISSN
0007-1250
e-ISSN
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Svazek periodika
206
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
6
Strana od-do
52-57
Kód UT WoS článku
000349656200010
EID výsledku v databázi Scopus
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