Impact of Body Mass Index on Long-Term Clinical Outcomes After Second-Generation Drug Eluting Stent Implantation: Insights From the International Global RESOLUTE Program

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F15%3A43909683" target="_blank" >RIV/00216208:11120/15:43909683 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064173:_____/15:N0000003

Výsledek na webu

<a href="http://dx.doi.org/10.1002/ccd.25828" target="_blank" >http://dx.doi.org/10.1002/ccd.25828</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/ccd.25828" target="_blank" >10.1002/ccd.25828</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impact of Body Mass Index on Long-Term Clinical Outcomes After Second-Generation Drug Eluting Stent Implantation: Insights From the International Global RESOLUTE Program

Popis výsledku v původním jazyce

BackgroundAn increased body mass index (BMI) is associated with a high risk of cardiovascular disease and reduction in life expectancy. However, several studies reported improved clinical outcomes in obese patients treated for cardiovascular diseases. The aim of the present study is to investigate the impact of BMI on long-term clinical outcomes after implantation of zotarolimus eluting stents. MethodsIndividual patient data were pooled from the RESOLUTE Clinical Program comprising five trials worldwide. The study population was sorted according to BMI tertiles and clinical outcomes were evaluated at 2-year follow-up. ResultsData from a total of 5,127 patients receiving the R-ZES were included in the present study. BMI tertiles were as follow: I tertile ( 25.95 kg/m(2)Low or normal weight) 1,727 patients; II tertile (>25.9529.74 kg/m(2)overweight) 1,695 patients, and III tertile (>29.74 kg/m(2)obese) 1,705 patients. At 2-years follow-up no difference was found for patients with high BM

Název v anglickém jazyce

Impact of Body Mass Index on Long-Term Clinical Outcomes After Second-Generation Drug Eluting Stent Implantation: Insights From the International Global RESOLUTE Program

Popis výsledku anglicky

BackgroundAn increased body mass index (BMI) is associated with a high risk of cardiovascular disease and reduction in life expectancy. However, several studies reported improved clinical outcomes in obese patients treated for cardiovascular diseases. The aim of the present study is to investigate the impact of BMI on long-term clinical outcomes after implantation of zotarolimus eluting stents. MethodsIndividual patient data were pooled from the RESOLUTE Clinical Program comprising five trials worldwide. The study population was sorted according to BMI tertiles and clinical outcomes were evaluated at 2-year follow-up. ResultsData from a total of 5,127 patients receiving the R-ZES were included in the present study. BMI tertiles were as follow: I tertile ( 25.95 kg/m(2)Low or normal weight) 1,727 patients; II tertile (>25.9529.74 kg/m(2)overweight) 1,695 patients, and III tertile (>29.74 kg/m(2)obese) 1,705 patients. At 2-years follow-up no difference was found for patients with high BM

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

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Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Catheterization &amp; Cardiovascular Interventions

ISSN

1522-1946

e-ISSN

—

Svazek periodika

85

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

952-958

Kód UT WoS článku

000353360800005

EID výsledku v databázi Scopus

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