Chapter One - Evolutionary origins of chemical synapses

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F20%3A43920282" target="_blank" >RIV/00216208:11120/20:43920282 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/bs.vh.2020.04.009" target="_blank" >https://doi.org/10.1016/bs.vh.2020.04.009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/bs.vh.2020.04.009" target="_blank" >10.1016/bs.vh.2020.04.009</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Chapter One - Evolutionary origins of chemical synapses

Popis výsledku v původním jazyce

Synaptic transmission is a fundamental neurobiological process by which neurons interact with each other and non-neuronal cells. It involves release of active substances from the presynaptic neuron onto receptive elements of postsynaptic cells, inducing waves of spreading electrochemical response. While much has been learned about the cellular and molecular mechanisms driving and governing transmitter release and sensing, the evolutionary origin of synaptic connections remains obscure. Herein, we review emerging evidence and concepts suggesting that key components of chemical synapse arose independently from neurons, in different functional and biological contexts, before the rise of multicellular living forms. We argue that throughout evolution, distinct synaptic constituents have been co-opted from ancestral forms for a new role in early metazoan, leading to the rise of chemical synapses and neurotransmission. Such a mosaic model of the origin of chemical synapses agrees with and supports the pluralistic hypothesis of evolutionary change.

Název v anglickém jazyce

Chapter One - Evolutionary origins of chemical synapses

Popis výsledku anglicky

Synaptic transmission is a fundamental neurobiological process by which neurons interact with each other and non-neuronal cells. It involves release of active substances from the presynaptic neuron onto receptive elements of postsynaptic cells, inducing waves of spreading electrochemical response. While much has been learned about the cellular and molecular mechanisms driving and governing transmitter release and sensing, the evolutionary origin of synaptic connections remains obscure. Herein, we review emerging evidence and concepts suggesting that key components of chemical synapse arose independently from neurons, in different functional and biological contexts, before the rise of multicellular living forms. We argue that throughout evolution, distinct synaptic constituents have been co-opted from ancestral forms for a new role in early metazoan, leading to the rise of chemical synapses and neurotransmission. Such a mosaic model of the origin of chemical synapses agrees with and supports the pluralistic hypothesis of evolutionary change.

Druh

C - Kapitola v odborné knize

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Hormones and Synapse

ISBN

978-0-12-822025-2

Počet stran výsledku

21

Strana od-do

1-21

Počet stran knihy

346

Název nakladatele

Elsevier

Místo vydání

New York

Kód UT WoS kapitoly

000612641100002