The effect of hyperbaric oxygen therapy on acute wound healing in rabbits: An experimental study and histopathological analysis
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11120%2F21%3A43921325" target="_blank" >RIV/00216208:11120/21:43921325 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/60162694:G44__/21:00556854
Výsledek na webu
<a href="https://doi.org/10.31482/mmsl.2021.001" target="_blank" >https://doi.org/10.31482/mmsl.2021.001</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.31482/mmsl.2021.001" target="_blank" >10.31482/mmsl.2021.001</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The effect of hyperbaric oxygen therapy on acute wound healing in rabbits: An experimental study and histopathological analysis
Popis výsledku v původním jazyce
Background: The goal of our research is to show the effects and impacts of hyperbaric oxygen therapy (HBOT) on acute model wounds in animal subjects. Methods: Three experimental groups were created using injured rabbits (N=36)-randomly divided into three groups (N=12 per group). One group was treated only with standard wound care management. Two groups were additionally treated with HBOT either once or twice a day. The wounds were surgical, uninfected, and in healthy animal test subjects. We compared the immunohistochemical and histological parameters in 4-, 7-and 10-day intervals. Results: The detection of epidermal leaf parameters, the number of microabscesses, the Histopathological Superficial Epithelium Healing Score, Connective Tissue Healing Score, Histopathological Acute Inflammation Score and Total Histopathological Wound Healing Score all showed significant changes between time intervals within the individual groups. Conclusion: The results did not show that HBOT had a significant effect on the healing process of uncomplicated acute wounds.
Název v anglickém jazyce
The effect of hyperbaric oxygen therapy on acute wound healing in rabbits: An experimental study and histopathological analysis
Popis výsledku anglicky
Background: The goal of our research is to show the effects and impacts of hyperbaric oxygen therapy (HBOT) on acute model wounds in animal subjects. Methods: Three experimental groups were created using injured rabbits (N=36)-randomly divided into three groups (N=12 per group). One group was treated only with standard wound care management. Two groups were additionally treated with HBOT either once or twice a day. The wounds were surgical, uninfected, and in healthy animal test subjects. We compared the immunohistochemical and histological parameters in 4-, 7-and 10-day intervals. Results: The detection of epidermal leaf parameters, the number of microabscesses, the Histopathological Superficial Epithelium Healing Score, Connective Tissue Healing Score, Histopathological Acute Inflammation Score and Total Histopathological Wound Healing Score all showed significant changes between time intervals within the individual groups. Conclusion: The results did not show that HBOT had a significant effect on the healing process of uncomplicated acute wounds.
Klasifikace
Druh
J<sub>SC</sub> - Článek v periodiku v databázi SCOPUS
CEP obor
—
OECD FORD obor
30305 - Occupational health
Návaznosti výsledku
Projekt
—
Návaznosti
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Ostatní
Rok uplatnění
2021
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Vojenské zdravotnické listy / Military Medical Science Letters
ISSN
0372-7025
e-ISSN
—
Svazek periodika
90
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
10
Strana od-do
2-11
Kód UT WoS článku
—
EID výsledku v databázi Scopus
2-s2.0-85102836855