Obesity is associated with worse oncological outcomes in patients treated with radical cystectomy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F13%3A10209789" target="_blank" >RIV/00216208:11130/13:10209789 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064203:_____/13:10209789

Výsledek na webu

<a href="http://dx.doi.org/10.1111/j.1464-410X.2012.11322.x" target="_blank" >http://dx.doi.org/10.1111/j.1464-410X.2012.11322.x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1464-410X.2012.11322.x" target="_blank" >10.1111/j.1464-410X.2012.11322.x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Obesity is associated with worse oncological outcomes in patients treated with radical cystectomy

Popis výsledku v původním jazyce

What's known on the subject? and What does the study add? Little is known on the association between obesity and urothelial carcinoma of the bladder (UCB). Most studies have shown that higher body mass index (BMI) is associated with higher rates of perioperative complications. Only one study specifically investigated obesity and bladder cancer-specific outcomes and reported no significant association between higher BMI and disease-specific survival in patients with UCB treated with radical cystectomy. However, that study was limited by its small sample size and a high rate of preoperative therapies. In contrast to the only previous study evaluating the association of BMI with oncological outcomes in UCB, we found that obesity (BMI 30kg/m2) was associated with features of biologically aggressive UCB and clinical outcomes after radical cystectomy and, even when adjusting for the effects of standard clinicopathological features, obesity remained an independent predictor of cancer recurren

Název v anglickém jazyce

Obesity is associated with worse oncological outcomes in patients treated with radical cystectomy

Popis výsledku anglicky

What's known on the subject? and What does the study add? Little is known on the association between obesity and urothelial carcinoma of the bladder (UCB). Most studies have shown that higher body mass index (BMI) is associated with higher rates of perioperative complications. Only one study specifically investigated obesity and bladder cancer-specific outcomes and reported no significant association between higher BMI and disease-specific survival in patients with UCB treated with radical cystectomy. However, that study was limited by its small sample size and a high rate of preoperative therapies. In contrast to the only previous study evaluating the association of BMI with oncological outcomes in UCB, we found that obesity (BMI 30kg/m2) was associated with features of biologically aggressive UCB and clinical outcomes after radical cystectomy and, even when adjusting for the effects of standard clinicopathological features, obesity remained an independent predictor of cancer recurren

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BJU International

ISSN

1464-4096

e-ISSN

—

Svazek periodika

111

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

249-255

Kód UT WoS článku

000315030200013

EID výsledku v databázi Scopus

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