Acid-base disorders associated with serum electrolyte patterns in patients on hemodiafiltration

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10316394" target="_blank" >RIV/00216208:11130/15:10316394 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11140/15:10316394 RIV/00064203:_____/15:10316394

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.nephro.2015.04.008" target="_blank" >http://dx.doi.org/10.1016/j.nephro.2015.04.008</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.nephro.2015.04.008" target="_blank" >10.1016/j.nephro.2015.04.008</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Acid-base disorders associated with serum electrolyte patterns in patients on hemodiafiltration

Popis výsledku v původním jazyce

Background. - Metabolic acidosis (MAC) is a common aspect of dialysis-dependent patients. It is definitely caused by acid retention; however, the influence of other plasma ions is unclear. Understanding the mechanism of MAC and its correction is important when choosing the dialysis solution. Therefore, we assessed the relationship between intradialytic change of acid-base status and serum electrolytes. Methods. - We studied 68 patients on post-dilution hemodiafiltration, using dialysate bicarbonate concentration 32 mmol/L. The acid-base disorders were evaluated by the traditional Siggaard-Anderson and modern Stewart approaches. Results. - The mean pre-dialysis pH was 7.38, standard base excess (SBE) -1.5, undetermined anions (UA-) 7.5, sodium-chloridedifference (Diff(NaCl)) 36.2 mmol/L. MAC was present in 34% of patients, of which 83% had an increased UA- as a major cause of MAC. The mean nPCR was 0.99 g/kg/day and correlated negatively with SBE. After dialysis, metabolic alkalosis pr

Název v anglickém jazyce

Acid-base disorders associated with serum electrolyte patterns in patients on hemodiafiltration

Popis výsledku anglicky

Background. - Metabolic acidosis (MAC) is a common aspect of dialysis-dependent patients. It is definitely caused by acid retention; however, the influence of other plasma ions is unclear. Understanding the mechanism of MAC and its correction is important when choosing the dialysis solution. Therefore, we assessed the relationship between intradialytic change of acid-base status and serum electrolytes. Methods. - We studied 68 patients on post-dilution hemodiafiltration, using dialysate bicarbonate concentration 32 mmol/L. The acid-base disorders were evaluated by the traditional Siggaard-Anderson and modern Stewart approaches. Results. - The mean pre-dialysis pH was 7.38, standard base excess (SBE) -1.5, undetermined anions (UA-) 7.5, sodium-chloridedifference (Diff(NaCl)) 36.2 mmol/L. MAC was present in 34% of patients, of which 83% had an increased UA- as a major cause of MAC. The mean nPCR was 0.99 g/kg/day and correlated negatively with SBE. After dialysis, metabolic alkalosis pr

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

—

Projekt

<a href="/cs/project/ED2.1.00%2F03.0076" target="_blank" >ED2.1.00/03.0076: Biomedicínské centrum Lékařské fakulty v Plzni</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nephrologie et Therapeutique

ISSN

1769-7255

e-ISSN

—

Svazek periodika

11

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

FR - Francouzská republika

Počet stran výsledku

7

Strana od-do

551-557

Kód UT WoS článku

000367869700004

EID výsledku v databázi Scopus

2-s2.0-84949556401