Increased prevalence and resistance of important pathogens recovered from respiratory specimens of cystic fibrosis patients during a decade
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10316861" target="_blank" >RIV/00216208:11130/15:10316861 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00064203:_____/15:10316861
Výsledek na webu
<a href="http://dx.doi.org/10.1097/INF.0000000000000714" target="_blank" >http://dx.doi.org/10.1097/INF.0000000000000714</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1097/INF.0000000000000714" target="_blank" >10.1097/INF.0000000000000714</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Increased prevalence and resistance of important pathogens recovered from respiratory specimens of cystic fibrosis patients during a decade
Popis výsledku v původním jazyce
Background: The study objective was to identify changes of prevalence and resistance of important pathogens in specimens of cystic fibrosis (CF) patients within a decade. Methods: Samples of 94 patients, who attended 2 CF centers from 2001 to 2011 were retrospectively analyzed. Results: Staphylococcus aureus was the most prevalent organism (74.5% in 2011) with an increase of methicillin-resistant S. aureus in patients (0% vs. 9.6%, n = 9). Resistance of S. aureus to gentamicin decreased (41.8% vs. 21%;P < 0.001), whereas resistance to rifampicin and trimethoprim/sulfamethoxazole (P < 0.05) increased significantly with a trend to increased resistance to clindamycin and erythromycin (P = 0.063). Methicillin-resistant S. aureus isolates belonged to 6 spatypes (t003, t008, t011, t034, t045, t548). There was a significant increase of Pseudomonas aeruginosa prevalence (63.8% in 2011 vs. 46.8% in 2001, P = 0.019). Resistance of P. aeruginosa increased significantly to imipenem, gentamicin,
Název v anglickém jazyce
Increased prevalence and resistance of important pathogens recovered from respiratory specimens of cystic fibrosis patients during a decade
Popis výsledku anglicky
Background: The study objective was to identify changes of prevalence and resistance of important pathogens in specimens of cystic fibrosis (CF) patients within a decade. Methods: Samples of 94 patients, who attended 2 CF centers from 2001 to 2011 were retrospectively analyzed. Results: Staphylococcus aureus was the most prevalent organism (74.5% in 2011) with an increase of methicillin-resistant S. aureus in patients (0% vs. 9.6%, n = 9). Resistance of S. aureus to gentamicin decreased (41.8% vs. 21%;P < 0.001), whereas resistance to rifampicin and trimethoprim/sulfamethoxazole (P < 0.05) increased significantly with a trend to increased resistance to clindamycin and erythromycin (P = 0.063). Methicillin-resistant S. aureus isolates belonged to 6 spatypes (t003, t008, t011, t034, t045, t548). There was a significant increase of Pseudomonas aeruginosa prevalence (63.8% in 2011 vs. 46.8% in 2001, P = 0.019). Resistance of P. aeruginosa increased significantly to imipenem, gentamicin,
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
EE - Mikrobiologie, virologie
OECD FORD obor
—
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Pediatric Infectious Disease Journal
ISSN
0891-3668
e-ISSN
—
Svazek periodika
34
Číslo periodika v rámci svazku
7
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
6
Strana od-do
700-705
Kód UT WoS článku
000369586900007
EID výsledku v databázi Scopus
2-s2.0-84942764951